Guo R, Tian J, Jia Y, He P F, Jin R X, Guo J, Wang B Q
Department of Otorhinolaryngology Head and Neck Surgery, the First Hospital, Shanxi Medical University, Shanxi Key Laboratory of Otorhinolaryngology Head and Neck Cancer, Key Institute and Laboratory of Otolaryngology affiliated with Shanxi Province, Taiyuan 030001, China.
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2017 Nov 7;52(11):876-880. doi: 10.3760/cma.j.issn.1673-0860.2017.11.020.
The lymphatic system plays an important role in human health and disease. In addition to a role in the immune response, the lymphatics can also serve as a pathway for cancer metastasis.Head and neck squamous cell carcinoma (HNSCC) is one of the most common cancers.In the case where the primary focus has been controlled, cervical lymph node metastasis is one of the most important factors affecting the prognosis of head and neck cancer.Thus, understanding the anatomy of the lymphatic system is of paramount importance in predicting cancer metastasis and to perform proper lymph node dissection in cancer patients.The objective of this review is to summarize current imaging approaches that facilitate both basic science and clinical investigations of lymphatic vasculature.Mutation analysis of the laryngeal lymphatic system may provide a theoretical basis for the diagnosis and treatment of HNSCC.
淋巴系统在人类健康和疾病中发挥着重要作用。除了在免疫反应中发挥作用外，淋巴管还可作为癌症转移的途径。头颈部鳞状细胞癌（HNSCC）是最常见的癌症之一。在原发灶得到控制的情况下，颈部淋巴结转移是影响头颈部癌症预后的最重要因素之一。因此，了解淋巴系统的解剖结构对于预测癌症转移以及在癌症患者中进行适当的淋巴结清扫至关重要。本综述的目的是总结有助于淋巴脉管系统基础科学和临床研究的当前成像方法。喉淋巴系统的突变分析可能为HNSCC的诊断和治疗提供理论依据。
