Hatemi Ibrahim, Hatemi Gulen, Çelik Aykut Ferhat
Division of Gastroenterology, Department of Internal Medicine, Cerrahpasa Medical School, Istanbul University, Koca Mustafa Pasa Mahallesi, Cerrahpaşa Caddesi No:53, 34096 Fatih/Istanbul, Turkey.
Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical School, Istanbul University, Koca Mustafa Paşa Mahallesi, Cerrahpasa Caddesi No:53, 34096 Fatih/Istanbul, Turkey.
Rheum Dis Clin North Am. 2018 Feb;44(1):45-64. doi: 10.1016/j.rdc.2017.09.007.
Behçet disease (BD) is a variable vessel vasculitis that can involve several organs and systems. Gastrointestinal (GI) involvement has an acute exacerbating course with ulcers, most commonly in the ileocolonic area. These ulcers can be large and deep, causing perforation and massive bleeding. This article highlights the current knowledge on the epidemiology, clinical findings, diagnosis, and management of GI involvement of BD, with emphasis on recent findings.
白塞病(BD)是一种可累及多个器官和系统的可变型血管炎。胃肠道受累时病程呈急性加重,伴有溃疡,最常见于回结肠区域。这些溃疡可能大而深,导致穿孔和大量出血。本文重点介绍了白塞病胃肠道受累的流行病学、临床表现、诊断和治疗方面的现有知识,并着重阐述了近期的研究发现。