Cvetanovich Gregory L, Weber Alexander E, Kuhns Benjamin D, Alter Jennifer, Harris Joshua D, Mather Richard C, Nho Shane J
Department of Orthopedic Surgery, Rush University Medical Center, Chicago, Illinois, USA.
Division of Sports Medicine, Department of Orthopaedic Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Am J Sports Med. 2018 Feb;46(2):288-296. doi: 10.1177/0363546517739824. Epub 2017 Nov 21.
There has been increasing interest in defining clinically meaningful outcomes in patient reported outcomes following orthopaedic surgery. Little is known about the factors associated with clinically meaningful outcomes after hip arthroscopy for femoroacetabular impingement.
Case-control study; Level of evidence, 3.
To report on a large, prospectively collected consecutive series of patients who underwent comprehensive arthroscopic treatment of femoroacetabular impingement (FAI) and capsular management with greater than 2-year follow-up. The objectives were to determine (1) what percentage of patients achieve clinically significant outcomes after hip arthroscopic surgery for FAI as determined by the minimal clinically important difference (MCID) and patient acceptable symptom state (PASS) and (2) what factors are associated with achieving the MCID and PASS.
Data from an institutional repository of consecutive patients undergoing primary hip arthroscopic surgery with routine capsular closure for FAI that had failed nonsurgical management between January 2012 and January 2014 were prospectively collected and analyzed. Of 474 patients during the enrollment period, 386 (81.4%) patients were available for a minimum 2-year follow-up. Demographics, radiographic measurements, intraoperative characteristics, and patient-reported outcome scores were collected. The primary outcome measure was achieving published thresholds for the MCID and PASS for the Hip Outcome Score (HOS)-Activities of Daily Living (ADL) in patients with FAI. The HOS-Sport-Specific Subscale (SSS), complications, and reoperations were secondary outcome measures. Multivariate regression analyses were conducted to identify factors associated with achieving the MCID and PASS.
At a minimum of 2-year follow-up, the patients had statistically significant improvements in all patient-reported outcomes (HOS-ADL, HOS-SSS, and modified Harris Hip Score [mHHS]; P < .001 for all), with a 1.2% rate of revision hip arthroscopic surgery and 1.7% rate of conversion to total hip arthroplasty. The MCID was achieved by 78.8% of patients for the HOS-ADL, and the PASS was achieved by 62.5% for the HOS-ADL. Younger age ( P = .008), Tönnis grade 0 ( P = .022), and lower preoperative HOS-ADL score ( P < .001) were associated with successfully achieving the MCID for the HOS-ADL. Younger age ( P < .001), larger medial joint space width ( P = .028), and higher preoperative HOS-ADL score ( P < .001) were associated with achieving the PASS for the HOS-ADL. Younger age ( P < .001), lower body mass index ( P = .006), non-workers' compensation status ( P = .020), and lower preoperative HOS-SSS score ( P < .001) were associated with achieving the MCID for the HOS-SSS. Younger age ( P = .001), Tönnis grade 0 ( P = .014), running ( P = .008), and higher preoperative HOS-SSS score ( P < .001) were associated with achieving the PASS for the HOS-SSS. Overall, 49.4% of patients achieved all 4 clinically significant outcomes: both the MCID and PASS for the HOS-ADL and HOS-SSS.
The majority of patients undergoing hip arthroscopic surgery with routine capsular closure for FAI experienced clinically significant outcomes that met the MCID or PASS criteria, with low rates of revision and conversion to total hip arthroplasty. Factors associated with these successful outcomes on multivariate analyses included younger age with a normal joint space. Patients with lower preoperative HOS scores were more likely to achieve the MCID, whereas patients with higher preoperative HOS scores were more likely to achieve the PASS.
在骨科手术后患者报告的结局中,确定具有临床意义的结局越来越受到关注。关于髋关节镜治疗股骨髋臼撞击症后具有临床意义的结局相关因素知之甚少。
病例对照研究;证据等级,3级。
报告一大组前瞻性收集的连续患者系列,这些患者接受了股骨髋臼撞击症(FAI)的综合关节镜治疗和关节囊处理,随访时间超过2年。目的是确定:(1)根据最小临床重要差异(MCID)和患者可接受症状状态(PASS),髋关节镜手术治疗FAI后达到临床显著结局的患者百分比;(2)与达到MCID和PASS相关的因素。
前瞻性收集并分析2012年1月至2014年1月期间因FAI接受初次髋关节镜手术并常规缝合关节囊且非手术治疗失败的连续患者的机构数据库中的数据。在入组期间的474例患者中,386例(81.4%)患者可进行至少2年的随访。收集人口统计学、影像学测量、术中特征和患者报告的结局评分。主要结局指标是达到FAI患者髋关节结局评分(HOS)-日常生活活动(ADL)的MCID和PASS的已发表阈值。HOS-运动特定子量表(SSS)、并发症和再次手术是次要结局指标。进行多变量回归分析以确定与达到MCID和PASS相关的因素。
至少2年随访时,所有患者报告的结局(HOS-ADL、HOS-SSS和改良Harris髋关节评分[mHHS])均有统计学显著改善(所有P <.001),髋关节镜翻修手术率为1.2%,转为全髋关节置换术率为1.7%。78.8%的患者HOS-ADL达到MCID,62.5%的患者HOS-ADL达到PASS。年龄较小(P =.008)、Tönnis分级0级(P =.022)和术前HOS-ADL评分较低(P <.001)与成功达到HOS-ADL的MCID相关。年龄较小(P <.001)、内侧关节间隙宽度较大(P =.028)和术前HOS-ADL评分较高(P <.001)与达到HOS-ADL的PASS相关。年龄较小(P <.001)、体重指数较低(P =.006)、非工伤赔偿状态(P =.020)和术前HOS-SSS评分较低(P <.001)与达到HOS-SSS的MCID相关。年龄较小(P =.001)、Tönnis分级0级(P =.014)、跑步(P =.008)和术前HOS-SSS评分较高(P <.001)与达到HOS-SSS的PASS相关。总体而言,49.4%的患者达到了所有4个临床显著结局:HOS-ADL和HOS-SSS的MCID和PASS。
大多数因FAI接受髋关节镜手术并常规缝合关节囊的患者经历了符合MCID或PASS标准的临床显著结局,翻修和转为全髋关节置换术的发生率较低。多变量分析中与这些成功结局相关的因素包括年龄较小且关节间隙正常。术前HOS评分较低的患者更有可能达到MCID,而术前HOS评分较高的患者更有可能达到PASS。