Nikkilä M T, Saaristo J J, Koivula T A
Department of Surgery, Tampere University Central Hospital, Finland.
Surgery. 1989 Feb;105(2 Pt 1):148-53.
Sixty-one consecutive patients were examined to determine the current mode of presentation of primary hyperparathyroidism (pHPT). Of these patients, 37.7% were asymptomatic, and the initial indication of pHPT was hypercalcemia, which was found unexpectedly on biochemical screening of the serum in elderly patients. Hypertension was twice as common among patients with pHPT as in the general population (36.1%). The next most common presentations were urinary calculi (18%) and mental depression (18%). The most useful discriminant laboratory tests were serum calcium, phosphorus, chloride, and parathormone (PTH). The calculated coefficient of correlation of PTH to land weight was high (r = 0.571, p less than 0.001). There was very significant correlation between PTH and seriousness of bone disease (r = 0.620, p less than 0.001). After parathyroidectomy, 3.3% of patients remained hypercalcemic, 93% were normocalcemic, and 1.6% were hypocalcemic.
对61例连续性患者进行检查，以确定原发性甲状旁腺功能亢进症（pHPT）当前的表现形式。在这些患者中，37.7%无症状，pHPT的最初指征是高钙血症，这是在老年患者血清生化筛查时意外发现的。pHPT患者中高血压的发生率是普通人群的两倍（36.1%）。接下来最常见的表现是尿路结石（18%）和精神抑郁（18%）。最有用的鉴别性实验室检查是血清钙、磷、氯和甲状旁腺激素（PTH）。计算得出PTH与陆地重量的相关系数很高（r = 0.571，p小于0.001）。PTH与骨病严重程度之间存在非常显著的相关性（r = 0.620，p小于0.001）。甲状旁腺切除术后，3.3%的患者仍有高钙血症，93%血钙正常，1.6%有低钙血症。
