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Re-evaluating evolution in the HIV reservoir.
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Genetically Intact but Functionally Impaired HIV-1 Env Glycoproteins in the T-Cell Reservoir.
J Virol. 2018 Jan 30;92(4). doi: 10.1128/JVI.01684-17. Print 2018 Feb 15.
3
The lymphocyte HIV reservoir in patients on long-term HAART is a memory of virus evolution.
AIDS. 2004 May 21;18(8):1147-58. doi: 10.1097/00002030-200405210-00008.
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A long-term latent reservoir for HIV-1: discovery and clinical implications.
J Antimicrob Chemother. 2004 Jul;54(1):6-9. doi: 10.1093/jac/dkh292. Epub 2004 May 26.
7
Cyclosporine A in addition to standard ART during primary HIV-1 infection: pilot randomized clinical trial.
J Antimicrob Chemother. 2017 Mar 1;72(3):829-836. doi: 10.1093/jac/dkw462.

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Applications and limitations of the passenger hypothesis for HIV reservoir persistence and cure.
J Virol. 2025 Jul 22;99(7):e0071425. doi: 10.1128/jvi.00714-25. Epub 2025 Jun 4.
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SIV proviruses seeded later in infection are harbored in short-lived CD4 T cells.
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No evidence for ongoing replication on ART in SIV-infected macaques.
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Modeling resistance to the broadly neutralizing antibody PGT121 in people living with HIV-1.
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Last in first out: SIV proviruses seeded later in infection are harbored in short-lived CD4 T cells.
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HIV Infection: Shaping the Complex, Dynamic, and Interconnected Network of the Cytoskeleton.
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Controversies in the Design of Strategies for the Cure of HIV Infection.
Pathogens. 2023 Feb 15;12(2):322. doi: 10.3390/pathogens12020322.
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Genotypic and Phenotypic Diversity of the Replication-Competent HIV Reservoir in Treated Patients.
Microbiol Spectr. 2022 Aug 31;10(4):e0078422. doi: 10.1128/spectrum.00784-22. Epub 2022 Jun 30.
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Antiretroviral drug exposure in lymph nodes is heterogeneous and drug dependent.
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本文引用的文献

2
Establishment and stability of the latent HIV-1 DNA reservoir.
Elife. 2016 Nov 15;5:e18889. doi: 10.7554/eLife.18889.
3
Persistent HIV-1 replication maintains the tissue reservoir during therapy.
Nature. 2016 Feb 4;530(7588):51-56. doi: 10.1038/nature16933. Epub 2016 Jan 27.
4
Residual Viremia in Treated HIV+ Individuals.
PLoS Comput Biol. 2016 Jan 6;12(1):e1004677. doi: 10.1371/journal.pcbi.1004677. eCollection 2016 Jan.
5
Precise Quantitation of the Latent HIV-1 Reservoir: Implications for Eradication Strategies.
J Infect Dis. 2015 Nov 1;212(9):1361-5. doi: 10.1093/infdis/jiv218. Epub 2015 Apr 15.
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Intra-host evolutionary rates in HIV-1C env and gag during primary infection.
Infect Genet Evol. 2013 Oct;19:361-8. doi: 10.1016/j.meegid.2013.02.023. Epub 2013 Mar 20.
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Selection on the human immunodeficiency virus type 1 proteome following primary infection.
J Virol. 2006 Oct;80(19):9519-29. doi: 10.1128/JVI.00575-06.
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Molecular characterization of preintegration latency in human immunodeficiency virus type 1 infection.
J Virol. 2002 Sep;76(17):8518-31. doi: 10.1128/jvi.76.17.8518-8513.2002.
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Biphasic decay of latently infected CD4+ T cells in acute human immunodeficiency virus type 1 infection.
J Infect Dis. 2000 Dec;182(6):1636-42. doi: 10.1086/317615. Epub 2000 Nov 8.

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