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电切针联合球囊扩张与单纯球囊扩张治疗气管瘢痕性狭窄的比较。

Application of Electrocautery Needle Knife Combined with Balloon Dilatation versus Balloon Dilatation in the Treatment of Tracheal Fibrotic Scar Stenosis.

机构信息

Department of Respiratory and Critical Care Medicine, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.

Department of Respiratory and Critical Care Medicine, General Hospital of Shenyang Military Area Command, Shenyang, China.

出版信息

Respiration. 2018;95(3):182-187. doi: 10.1159/000484253. Epub 2017 Nov 23.

Abstract

BACKGROUND

Electrocautery needle knives can largely reduce scar and granulation tissue hyperplasia and play an important role in treating patients with benign stricture.

OBJECTIVE

The aim of this retrospective study was to evaluate the efficacy and safety of electrocautery needle knife combined with balloon dilatation versus balloon dilatation alone in the treatment of tracheal stenosis caused by tracheal intubation or tracheotomy.

METHODS

We retrospectively analysed the clinical data of 43 patients with tracheal stenosis caused by tracheotomy or tracheal intubation in our department from January 2013 to January 2016. Among these 43 patients, 23 had simple web-like stenosis and 20 had complex steno sis. All patients were treated under general anaesthesia, and the treatment methods were (1) balloon dilatation alone, (2) needle knife excision of fibrotic tissue combined with balloon dilatation, and (3) needle knife radial incision of fibrotic tissue combined with balloon dilatation.

RESULTS

After treatment the symptoms, such as shortness of breath, were markedly improved immediately in all cases. The stenosis degree of patients who were treated with the elec-trocautery needle knife combined with balloon dilatation had better improvement compared with that of those treated with balloon dilatation treatment alone after 3 months (0.45 ± 0.04 vs. 0.67 ± 0.05, p < 0.01), and the proportion of restenosis occurrence that required further treatment was decreased at 6 months (46.9 vs. 81.8%), especially for the web-like stenosis patients, as most of their stenoses dilated with no obvious restenosis and achieved clinical cure.

CONCLUSION

Electrocautery needle knife combined with balloon dilatation is an effective and safe treatment for tracheal fibrotic stenosis compared with balloon dilatation alone.

摘要

背景

电切针刀可明显减少瘢痕及肉芽组织增生,在治疗良性狭窄患者中发挥重要作用。

目的

本回顾性研究旨在评估电切针刀联合球囊扩张与单纯球囊扩张治疗气管插管或切开后所致气管狭窄的疗效和安全性。

方法

我们回顾性分析了 2013 年 1 月至 2016 年 1 月期间我科收治的 43 例气管切开或气管插管后所致气管狭窄患者的临床资料。43 例患者中单纯膜状狭窄 23 例,复杂狭窄 20 例。所有患者均在全身麻醉下进行治疗,治疗方法包括:(1)单纯球囊扩张;(2)电切针刀切除纤维组织联合球囊扩张;(3)电切针刀行纤维组织放射状切开联合球囊扩张。

结果

所有患者呼吸困难等症状在治疗后即刻均明显改善。治疗 3 个月后,电切针刀联合球囊扩张组患者的狭窄程度较单纯球囊扩张组改善更明显(0.45 ± 0.04 比 0.67 ± 0.05,p < 0.01),6 个月时需要进一步治疗的再狭窄发生率降低(46.9%比 81.8%),特别是膜状狭窄患者,多数狭窄扩张后无明显再狭窄,达到临床治愈。

结论

与单纯球囊扩张相比,电切针刀联合球囊扩张治疗气管纤维性狭窄是一种有效且安全的方法。

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