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麻醉与睡眠呼吸暂停。

Anesthesia and sleep apnea.

机构信息

Laboratoire HP2, Inserm 1042, Universitée Grenoble Alpes, Grenoble F-38042, France; Laboratoire EFCR et Sommeil, Pôle Thorax et Vaisseaux, Grenoble Alpes University Hospital, Grenoble 38043, France.

Pôle Anesthésie-réanimation - Hôpital Michallon, Grenoble Alpes University Hospital, Grenoble F-38000, France.

出版信息

Sleep Med Rev. 2018 Aug;40:79-92. doi: 10.1016/j.smrv.2017.10.006. Epub 2017 Nov 22.

Abstract

Due to its low rate of diagnosis, in the general population over half of those experiencing obstructive sleep apnea (OSA) are unaware that they have the condition. However, any acute medical event may exacerbate OSA and could have serious health consequences. In this context the management of the perioperative period, from anesthesia through the surgery itself and into the postoperative period, is more problematic for patients with sleep disordered breathing than for others. There is prolific literature in this area although large randomized trials are few due to the high sample size needed and possible ethical difficulties of withholding OSA treatment in the perioperative period. In 2014 the American Society of Anesthesiologists published an updated set of recommendations to guide OSA management during the perioperative period. In this present review we provide an overview of the different issues that practitioners face with regard to OSA, from the initial consultation with the anesthesiologist to the extended post-operative period. There is considerable evidence that OSA patients are at high risk of perioperative complications, though the inherent risks from OSA per se and its comorbidities remain difficult to discern. Nevertheless, appropriate screening and management allow clinicians to minimize OSA associated risk.

摘要

由于其诊断率低,在普通人群中,超过一半的阻塞性睡眠呼吸暂停(OSA)患者不知道自己患有这种疾病。然而,任何急性医疗事件都可能使 OSA 恶化,并可能产生严重的健康后果。在这种情况下,患有睡眠呼吸障碍的患者在围手术期的管理(从麻醉到手术本身再到术后)比其他患者更成问题。尽管由于需要大量样本和可能在围手术期隐瞒 OSA 治疗的伦理困难,大型随机试验很少,但该领域有大量文献。2014 年,美国麻醉师学会发布了一套新的建议,以指导围手术期的 OSA 管理。在本综述中,我们概述了从业者在初始咨询麻醉师到延长的术后期间,在 OSA 方面面临的不同问题。有大量证据表明 OSA 患者在围手术期并发症方面风险很高,尽管 OSA 本身及其合并症的固有风险仍然难以识别。然而,适当的筛查和管理可以让临床医生最大限度地降低与 OSA 相关的风险。

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