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开放手术与管状翻修显微椎间盘切除术术中意外硬脊膜切开术:一项关于发生率、处理及结局的回顾性对照研究

Incidental Durotomy in Open Versus Tubular Revision Microdiscectomy: A Retrospective Controlled Study on Incidence, Management, and Outcome.

作者信息

Kogias Evangelos, Klingler Jan-Helge, Franco Jimenez Pamela, Vasilikos Ioannis, Sircar Ronen, Scholz Christoph, Hubbe Ulrich

机构信息

Department of Neurosurgery, University Medical Center Freiburg, Freiburg, Germany.

出版信息

Clin Spine Surg. 2017 Dec;30(10):E1333-E1337. doi: 10.1097/BSD.0000000000000279.

Abstract

STUDY DESIGN

Retrospective case-control study.

OBJECTIVE

To compare the incidence, management, and outcome of incidental durotomy in revision microdiscectomy with open and minimal-access surgery.

SUMMARY OF BACKGROUND DATA

Incidental durotomy occurs with a variable incidence of 3%-27% in spine surgery. The highest rate occurs in revision microdiscectomy. The intraoperative and postoperative management of dural tears varies in the literature and the definite impact on clinical outcome has to be clarified.

METHODS

This is a retrospective study of medical records of 135 patients who underwent revision microdiscectomy, divided into 2 subgroups: OPEN (n=82) versus minimal-access surgery (MINI, n=53). Occurrence of intraoperative dural tears, intraoperative and postoperative management of durotomy, and clinical outcomes, according to MacNab criteria, were retrospectively examined. Statistical comparisons for categorical values between groups were accomplished using the 2-tailed Fisher exact test. P-values <0.05 were considered to be statistically significant.

RESULTS

The incidence of durotomy in group OPEN was 19.5% (n=16/82) and in group MINI 17.0% (n=9/53) (P=0.822). The majority of durotomies (23/25) were repaired with an absorbable fibrin sealant patch alone. Postoperative cerebrospinal fluid fistula occurred only in 1 case of the OPEN group and was treated with lumbar drainage without the need for a reoperation. Patients with durotomy of the MINI group tended to have better outcome compared with those of the OPEN group without being statistically significant.

CONCLUSIONS

The incidence of durotomy and postoperative cerebrospinal fluid fistula in lumbar revision microdiscectomy does not significantly differ between minimal-access and standard open procedures. The application of a fibrin sealant patch alone is an effective strategy for dural repair in revision lumbar microdiscectomy.

摘要

研究设计

回顾性病例对照研究。

目的

比较翻修显微椎间盘切除术采用开放手术和微创入路手术时意外硬脊膜切开的发生率、处理方法及结果。

背景资料总结

脊柱手术中意外硬脊膜切开的发生率为3% - 27%不等。最高发生率出现在翻修显微椎间盘切除术中。关于硬脊膜撕裂的术中及术后处理,文献报道不一,其对临床结果的确切影响有待明确。

方法

这是一项对135例行翻修显微椎间盘切除术患者的病历进行的回顾性研究,分为2个亚组:开放手术组(n = 82)和微创入路手术组(MINI,n = 53)。回顾性检查术中硬脊膜撕裂的发生情况、硬脊膜切开的术中及术后处理方法以及根据MacNab标准评估的临床结果。采用双侧Fisher精确检验对组间分类变量进行统计学比较。P值<0.05被认为具有统计学意义。

结果

开放手术组硬脊膜切开的发生率为19.5%(n = 16/82),微创入路手术组为17.0%(n = 9/53)(P = 0.822)。大多数硬脊膜切开(23/25)仅用可吸收纤维蛋白封闭剂贴片修复。脑脊液漏仅发生在开放手术组的1例患者中,经腰大池引流治疗,无需再次手术。微创入路手术组硬脊膜切开患者的预后与开放手术组相比倾向于更好,但无统计学意义。

结论

在腰椎翻修显微椎间盘切除术中,微创入路手术和标准开放手术在硬脊膜切开及术后脑脊液漏的发生率方面无显著差异。单纯应用纤维蛋白封闭剂贴片是翻修腰椎显微椎间盘切除术中硬脊膜修复的有效策略。

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