Tondorf Theresa, Kaufmann Lisa-Katrin, Degel Alexander, Locher Cosima, Birkhäuer Johanna, Gerger Heike, Ehlert Ulrike, Gaab Jens
Clinical Psychology and Psychotherapy, Department of Psychology, University of Basel, Basel, Switzerland.
Clinical Psychology and Psychotherapy, Institute of Psychology, University of Zurich, Zurich, Switzerland.
PLoS One. 2017 Nov 27;12(11):e0187400. doi: 10.1371/journal.pone.0187400. eCollection 2017.
Psychotherapy has been shown to be effective, but efforts to prove specific effects by placebo-controlled trials have been practically and conceptually hampered. We propose that adopting open/hidden designs from placebo research would offer a possible way to establish specificity in psychotherapy. Therefore, we tested the effects of providing opposing treatment rationales in an online expressive writing intervention on affect in healthy subjects. Results indicate that it was possible to conduct the expressive writing intervention both covertly and openly, but that participants in the hidden administration condition did not fully benefit from the otherwise effective expressive writing intervention in the long-run. Effect sizes between open and hidden administration groups were comparable to pre-post effect sizes of the intervention. While this finding is important for the understanding of psychotherapy's effects per se, it also proves that alternative research approaches to establish specificity are feasible and informative in psychotherapy research.
German Clinical Trials Register DRKS00009428.
心理治疗已被证明是有效的,但通过安慰剂对照试验来证明其特定效果的努力在实践和概念上都受到了阻碍。我们建议采用安慰剂研究中的开放/隐藏设计,这可能为确立心理治疗的特异性提供一种方法。因此,我们测试了在一项在线表达性写作干预中提供相反的治疗原理对健康受试者情绪的影响。结果表明,既可以秘密地也可以公开地进行表达性写作干预,但从长远来看,处于隐藏给药条件下的参与者并未充分受益于原本有效的表达性写作干预。开放给药组和隐藏给药组之间的效应大小与干预前后的效应大小相当。虽然这一发现对于理解心理治疗本身的效果很重要,但它也证明了在心理治疗研究中确立特异性的替代研究方法是可行且有参考价值的。
德国临床试验注册中心DRKS00009428 。