Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.
Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
J Trop Pediatr. 2018 Oct 1;64(5):434-437. doi: 10.1093/tropej/fmx083.
Disseminated cryptococcosis is infrequent in immunocompetent children. Pulmonary and central nervous system are the commonly involved sites of infection in an immunocompromised host. We report a fatal case of disseminated cryptococcosis in an immunocompetent host presenting as fever of unknown origin with miliary shadows on chest radiograph, mimicking tuberculosis. In countries with the heavy burden of tuberculosis, a high index of suspicion is needed for early diagnosis of its close mimics like disseminated cryptococcosis.
播散性隐球菌病在免疫功能正常的儿童中较为少见。在免疫功能低下的宿主中,肺部和中枢神经系统是常见的感染部位。我们报告了一例免疫功能正常的宿主发生播散性隐球菌病的致死性病例,该患者表现为原因不明的发热,胸片显示粟粒状阴影,类似于结核病。在结核病负担沉重的国家,需要高度怀疑其类似疾病,如播散性隐球菌病,以进行早期诊断。