Ionic Fluorination of Carbon Monoxide as a Route to Gasphase Carbonylation of Inert CH and NH Bonds.

Gaseous FCO ions from the ionization of mixtures of nitrogen trifluoride and carbon monoxide execute selective and efficient CO-functionalization of the C-H bonds of benzene and toluene and of the N-H bond of ammonia. The occurrence of these carbonylation reactions has been unambiguously ascertained by Fourier-transform ion cyclotron resonance (FT-ICR) spectrometry, and the details of the structure and the mechanism of formation of the precursor FCO ions have been investigated. FT-ICR experiments show that these ions, structurally assigned as F-C-O by collisionally activated dissociation (CAD) spectrometry, arise from the reaction of CO with NF and of NF with CO. Combining the latter F transfer with the independently observed fluoride-ion abstraction by FCO from NF results in a catalytic cycle in which gaseous NF ions promote the conversion of carbon monoxide into carbonic difluoride, F CO, with nitrogen trifluoride as the source of F.