Alidu H, Owiredu W K B A, Amidu N, Gyasi-Sarpong C K, Dapare P P M, Bawah A T, Obirikorang C, Luuse A T
Department of Medical Laboratory Science, University of Health and Allied Sciences, Ho, Ghana.
Department of Molecular Medicine, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Int J Impot Res. 2018 Feb;30(1):8-13. doi: 10.1038/s41443-017-0003-5. Epub 2017 Nov 27.
About 25% of the world's adult population suffers from arterial hypertension with about 1.5 billion estimated to develop hypertension by 2025. Hypertensive patients have been reported to have a higher risk of developing diabetes and sexual dysfunction. Hypertension have been linked with lubricative and orgasmic difficulties in females, as wel as ED and vascular disease in men. Obesity has also been linked to ED in diabetic males as well as several aspects of female sexuality. Hypertension and obesity are closely related, each occurring in greater frequency with the other, it is only logical to think that comorbidities of obesity and hypertension could increase the risk of cardiovascular disease and SD. This research looks at the relationship between hypertension and obesity comorbidities and its association with sexual function in type II diabetics. Diabetic patients who were at least 18 years old and were engaged in a stable heterosexual relationships for at least 1 year were recruited for this study. Participants were categorized into the -HYP/-OB, +HYP/-OB and the +HYP/+OB groups. Sexual function was assessed using the GRISS-M and GRIS-F for the diabetic males and females respectively. Early morning fasting blood samples was used in lipid profile as well as FBG assay. The Coronary risk was estimated as Total/HDL Cholesterol. Triglyceride levels and coronary risk were highest in the +HYP/+OBES group, followed by the +HYP/-OBES group, with the -HYP/-OBES group recording the lowest levels. PE and infrequency recorded the highest score among the +HYP/+OBES group with the +HYP/-OBES group recording the lowest scores. SQoL was highest amongst the -HYP/-OBES group, with the +HYP/+OBES group recording the lowest scores. Anorgasmia and avoidance increased along the shades of HYP/OBES groups. Comorbidities of hypertension and obesity increases the risk of coronary disease, affects some domains of sexual function and decreases the SQoL of diabetics.
全球约25%的成年人口患有动脉高血压，预计到2025年将有15亿人患高血压。据报道，高血压患者患糖尿病和性功能障碍的风险更高。高血压与女性润滑和性高潮困难以及男性勃起功能障碍和血管疾病有关。肥胖也与糖尿病男性的勃起功能障碍以及女性性功能的几个方面有关。高血压和肥胖密切相关，二者并发的频率都更高，因此认为肥胖和高血压的合并症可能会增加心血管疾病和性功能障碍的风险是合乎逻辑的。本研究探讨高血压和肥胖合并症之间的关系及其与II型糖尿病患者性功能的关联。本研究招募了至少18岁且处于稳定异性恋关系至少1年的糖尿病患者。参与者被分为-HYP/-OB、+HYP/-OB和+HYP/+OB组。分别使用GRISS-M和GRIS-F对糖尿病男性和女性的性功能进行评估。清晨空腹血样用于血脂分析以及空腹血糖检测。冠状动脉风险估计为总胆固醇/高密度脂蛋白胆固醇。+HYP/+OBES组的甘油三酯水平和冠状动脉风险最高，其次是+HYP/-OBES组，-HYP/-OBES组的水平最低。+HYP/+OBES组的早泄和性交频率低得分最高，+HYP/-OBES组得分最低。-HYP/-OBES组的性生活质量最高，+HYP/+OBES组得分最低。性高潮缺失和性回避在HYP/OBES组中呈上升趋势。高血压和肥胖的合并症会增加冠心病风险，影响性功能的某些方面，并降低糖尿病患者的性生活质量。
