Pullon S R, Reinken J A, Sparrow M J
Royal New Zealand College of General Practitioners, Wellington Faculty.
N Z Med J. 1989 Feb 22;102(862):72-4.
A survey of 1826 women in the Wellington region was carried out. Participants were asked about their general and gynaecological health, as well as detailed questions about their last menstrual cycle. The majority (1456) had had a menstrual period within the last month or so. Eighty five percent of these women noted premenstrual symptoms of some kind, and were asked about a variety of self-help measures, and medical help, for these, and whether the advice and/or treatment was in fact helpful. Nine hundred and ninety women had tried self-help while four hundred and sixteen had sought medical help. The most commonly tried self-help measures were exercise, rest and vitamin B6. Half the women had tried each of these. Overall, there was a marked placebo response, but exercise, rest and keeping a written diary of symptoms were all helpful in over eighty percent of those who tried them. Doctors offered a wide range of treatments, including vitamin B6, diuretics, oral contraceptives and mefanamic acid, but the effect of these was difficult to evaluate further. When the sample was subdivided into clusters of women who shared similar symptoms, significant differences in the effectiveness of different self help measures emerged. Four different premenstrual syndromes are suggested: PMS-breast, PMS-bloat, PMS-irritable and intolerant, and PMS-various.
对惠灵顿地区的1826名女性进行了一项调查。参与者被问及她们的一般健康状况和妇科健康状况,以及关于她们最后一个月经周期的详细问题。大多数(1456人)在过去一个月左右来过月经。这些女性中有85%表示有某种经前症状,并被问及针对这些症状的各种自助措施和医疗帮助,以及这些建议和/或治疗是否真的有帮助。990名女性尝试过自助,416名女性寻求过医疗帮助。最常尝试的自助措施是运动、休息和维生素B6。有一半的女性尝试过这些措施中的每一种。总体而言,存在明显的安慰剂反应,但运动、休息和记录症状日记对超过80%尝试过这些方法的人都有帮助。医生提供了多种治疗方法,包括维生素B6、利尿剂、口服避孕药和甲灭酸,但这些方法的效果难以进一步评估。当将样本细分为有相似症状的女性群体时,不同自助措施的有效性出现了显著差异。提出了四种不同的经前综合征:经前乳房综合征、经前腹胀综合征、经前易怒不耐受综合征和经前多种症状综合征。