帕金森病：血液转录组学在帕金森病中的应用？
Parkinson disease: Blood transcriptomics for Parkinson disease?
机构信息
Department of Neurology, University of Pennsylvania, 3 West Gates, 3400 Spruce Street, Philadelphia, Pennsylvania 19104, USA.
出版信息
Nat Rev Neurol. 2018 Jan;14(1):5-6. doi: 10.1038/nrneurol.2017.166. Epub 2017 Dec 1.
Abstract
Parkinson disease (PD) affects up to 10 million people worldwide and is clinically diagnosed. Molecular phenotyping of patient samples might help to corroborate diagnosis, and a new study suggests that blood-based gene expression profiling might distinguish between patients with PD and those without. However, experience suggests that additional replication is needed.
摘要
帕金森病（PD）影响全球多达 1000 万人，且可临床诊断。对患者样本进行分子表型分析可能有助于证实诊断，一项新研究表明，基于血液的基因表达谱分析或许可以区分 PD 患者和非 PD 患者。然而，经验表明，还需要进一步的复制。
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