Division of Infectious Disease, Department of Internal Medicine, Tungs' Taichung Metroharbor Hospital, Taichung, Taiwan.
Infection Control Centre, MacKay Memorial Hospital, Taipei, Taiwan.
J Microbiol Immunol Infect. 2019 Aug;52(4):592-597. doi: 10.1016/j.jmii.2017.11.001. Epub 2017 Dec 2.
BACKGROUND/PURPOSE: This study investigated the impact of implementing ventilator-associated pneumonia (VAP) bundle care on the rates of VAP in intensive care units (ICUs) in Taiwan.
A total of 10 ICUs (bed number, 170), including surgical (SICUs) (n = 7), cardiovascular/surgical (CV/S-ICUs) (n = 1), and medical ICUs (MICUs) (n = 2) from 10 hospitals (7 medical center hospitals and 3 regional hospitals) were enrolled in this quality-improvement project. This study was divided into the pre-intervention phase (1st January, 2012-31st July, 2013) and the intervention phase (1st August, 2013-31st October, 2014).
Among the 10 hospitals, the overall rates (cases per 1000 ventilator-days) of VAP declined significantly (p = 0.005; rate ratio, 0.71) from 1.9 in the pre-intervention period to 1.5 in the intervention period. Significant difference in VAP rates between these periods was found in the regional hospitals (from 1.6 to 0.7; p < 0.001) and the SICUs (from 2.1 to 1.4; p < 0.001), but not in the medical centers (2.0 vs. 1.9; p = 0.0667) or CV/S-ICUs (4.5 vs. 4.5; p = 0.5391). However, VAP rate increased significantly (cases per 1000 ventilator-days) in the MICUs between the two periods (from 0.5 to 1.0; p = 0.0489). For the VAP bundle care elements, the overall compliance rate was 87.7% with 83.6% and 97.9% in the medical centers and regional hospitals, respectively.
Implementing VAP bundle care has effectively reduced VAP in Taiwanese ICUs, but differences in performance and compliance rates of VAP bundle care among the different ICUs and hospital categories did exist.
背景/目的:本研究旨在探讨在台湾实施呼吸机相关性肺炎(VAP)集束化护理对重症监护病房(ICU)中 VAP 发生率的影响。
共纳入来自 10 家医院(7 家医学中心医院和 3 家区域医院)的 10 个 ICU(床位数量 170 张),包括外科重症监护病房(SICUs)(n=7)、心血管/外科重症监护病房(CV/S-ICUs)(n=1)和内科重症监护病房(MICUs)(n=2)。本研究分为干预前阶段(2012 年 1 月 1 日至 2013 年 7 月 31 日)和干预阶段(2013 年 8 月 1 日至 2014 年 10 月 31 日)。
在这 10 家医院中,VAP 的总体发生率(每 1000 个呼吸机使用日的病例数)从干预前的 1.9 显著下降(p=0.005;率比为 0.71)至干预后的 1.5。在区域医院(从 1.6 降至 0.7;p<0.001)和外科重症监护病房(从 2.1 降至 1.4;p<0.001)中,这两个时期的 VAP 发生率存在显著差异,但在医学中心(2.0 与 1.9;p=0.0667)或心血管/外科重症监护病房(4.5 与 4.5;p=0.5391)中则无显著差异。然而,在这两个时期,内科重症监护病房的 VAP 发生率显著增加(每 1000 个呼吸机使用日的病例数)(从 0.5 增至 1.0;p=0.0489)。对于 VAP 集束化护理要素,整体依从率为 87.7%,其中医学中心为 83.6%,区域医院为 97.9%。
在台湾,实施 VAP 集束化护理可有效降低 ICU 中 VAP 的发生率,但不同 ICU 和医院类别之间 VAP 集束化护理的执行情况和依从率存在差异。