Widespread spontaneous hyperproliferation, melanosis and melanoma in Hgf-Cdk4R24C mice.
作者信息
van der Weyden Louise, Arends Mark J, Brenn Thomas, Tuting Thomas, Adams David J
机构信息
Experimental Cancer Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge.
Centre for Comparative Pathology, Cancer Research UK Edinburgh Centre, Division of Pathology, Institute of Genetics and Molecular Medicine.
出版信息
Melanoma Res. 2018 Feb;28(1):76-78. doi: 10.1097/CMR.0000000000000414.
Abstract
摘要
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Autochthonous primary and metastatic melanomas in Hgf-Cdk4 R24C mice evade T-cell-mediated immune surveillance.Hgf-Cdk4 R24C 小鼠中的原发性和转移性黑色素瘤逃避 T 细胞介导的免疫监视。
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