Rais Meryem, Kessab Amine, Sayad Zahra, El Mourabit Sanae, Zrarqi Redallah, Benazzou Salma, Boulaadas Malik, Cherradi Nadia
Department of Pathology, Hospital of Specialities, Rabat, Morocco.
Faculty of Medicine and Pharmacy of Rabat, Mohammed V University in Rabat, Rabat, Morocco.
BMC Clin Pathol. 2017 Nov 21;17:22. doi: 10.1186/s12907-017-0062-z. eCollection 2017.
Solitary fibrous tumor is an uncommon spindle cell neoplasm of unknown origin. It has been reported in many anatomic sites, with a rare occurrence in the head and neck region. Solitary fibrous tumors of the parotid gland are exceptional; their clinical and radiologic features are non specific, often mimicking more common salivary gland tumors. Pathologic examination and immunohistochemistry are required to make the correct diagnosis. The prognosis is favorable, with most tumors being benign, and complete surgical resection is the treatment of choice.
We report the case of a 42-year-old man who presented with a painless mass involving the parotid gland. A parotidectomy was performed, and follow up was unremarkable. Gross examination showed a well circumscribed, firm tumor measuring 3,4 cm. Histologically, the tumor was composed of a spindle cell proliferation of variable cellularity, with staghorn vessels. A panel of immunohistochemical stains was performed, and confirmed the diagnosis of parotid gland solitary fibrous tumor.
In this report we aim to increase awareness of this rare entity among clinicians and pathologists, and to emphasize the role of immunohistochemistry in confirming the diagnosis.
孤立性纤维瘤是一种起源不明的罕见梭形细胞肿瘤。它在许多解剖部位均有报道，在头颈部区域罕见。腮腺孤立性纤维瘤更是罕见；其临床和放射学特征不具特异性，常与更常见的涎腺肿瘤相似。需要进行病理检查和免疫组化才能做出正确诊断。预后良好，大多数肿瘤为良性，完整手术切除是首选治疗方法。
我们报告一例42岁男性，其表现为腮腺无痛性肿块。进行了腮腺切除术，随访无异常。大体检查显示肿瘤边界清楚、质地硬，大小为3.4厘米。组织学上，肿瘤由细胞密度不一的梭形细胞增生构成，并伴有鹿角状血管。进行了一组免疫组化染色，确诊为腮腺孤立性纤维瘤。
在本报告中，我们旨在提高临床医生和病理学家对这种罕见疾病的认识，并强调免疫组化在确诊中的作用。
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