开始接受广泛耐药结核病治疗的患者的精神障碍与药物/酒精使用情况
Mental disorders and drug/alcohol use in patients commencing extensively drug-resistant tuberculosis treatment.
作者信息
Scuffell J, Boccia D, Garcia Velarde F, Leon S R, Raviola G, Lecca L, Galea J T
机构信息
Epsom and St Helier University Hospitals NHS Trust, London, UK.
Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK.
出版信息
Public Health Action. 2017 Sep 21;7(3):237-239. doi: 10.5588/pha.17.0044.
Abstract
Mental disorders and alcohol/drug use worsen treatment outcomes for multidrug-resistant tuberculosis (TB), but data are lacking for extensively drug-resistant (XDR) TB. We investigated the association of baseline mental disorders and alcohol/drug use on XDR-TB treatment outcomes in a retrospective study of 53 XDR-TB Peruvian patients during 2010-2012. Logistic regression estimated the odds ratios for unfavourable XDR-TB treatment outcomes. Overall treatment success was 25%. Mental disorders and drug/alcohol use were found in respectively 22.4% and 20.4% of patients; neither were associated with unfavourable treatment outcomes. Future research should explore the relationship between mental health and drug/alcohol use in XDR-TB treatment outcomes.
摘要
精神障碍和酒精/药物使用会使耐多药结核病（TB）的治疗结果恶化，但关于广泛耐药（XDR）结核病的数据却很缺乏。在一项对2010 - 2012年期间53例秘鲁XDR - TB患者的回顾性研究中，我们调查了基线精神障碍和酒精/药物使用与XDR - TB治疗结果之间的关联。逻辑回归估计了XDR - TB治疗结果不佳的比值比。总体治疗成功率为25%。分别在22.4%和20.4%的患者中发现了精神障碍和药物/酒精使用情况；两者均与治疗结果不佳无关。未来的研究应探索心理健康与XDR - TB治疗结果中药物/酒精使用之间的关系。
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