Jung Sangeun, Kim Mee Gang, Lee Jong In
Department of Rehabilitation Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Ann Rehabil Med. 2017 Oct;41(5):868-874. doi: 10.5535/arm.2017.41.5.868. Epub 2017 Oct 31.
To identify the prevalence of lumbar scoliosis in breast cancer patients and to investigate the potential risk factors of lumbar scoliosis.
A retrospective chart review was performed in breast cancer patients aged more than 40 years who underwent dual energy X-ray absorptiometry (DEXA) scanning between January 2014 and December 2014. We divided the patients into control and experimental groups in order to investigate the influence of breast cancer treatment. The curvature of the lumbar spine was measured by using the Cobb method on a DEXA scan. Scoliosis was defined by the presence of a curvature 10° or larger. The variables, including age, bone mineral density (BMD), body mass index (BMI), and breast cancer treatments, were also obtained from the medical chart. Prevalence of lumbar scoliosis was evaluated, and it was compared between the two groups. The relationships between lumbar scoliosis and these variables were also investigated.
Lumbar scoliosis was present in 16 out of our 652 breast cancer patients. There was no difference in the prevalence of lumbar scoliosis between the control group (7/316) and the experimental group (9/336) (p=0.70). According to the logistic regression analysis, lumbar scoliosis had no significant association with operation, chemotherapy, hormone therapy, BMI, and BMD (p>0.05). However, age showed a significant relationship with prevalence of lumbar scoliosis (p<0.001; odds ratio, 1.11; 95% confidence interval, 1.054-1.170).
Prevalence of lumbar scoliosis in patients with breast cancer was 2.45%. Lumbar scoliosis had no association with breast cancer treatments, BMD, and BMI. Age was the only factor related to the prevalence of lumbar scoliosis.
确定乳腺癌患者腰椎侧弯的患病率，并调查腰椎侧弯的潜在危险因素。
对2014年1月至2014年12月期间接受双能X线吸收测定法（DEXA）扫描的40岁以上乳腺癌患者进行回顾性病历审查。为了研究乳腺癌治疗的影响，我们将患者分为对照组和实验组。在DEXA扫描上使用Cobb法测量腰椎的曲度。脊柱侧弯定义为存在10°或更大的曲度。还从病历中获取了包括年龄、骨矿物质密度（BMD）、体重指数（BMI）和乳腺癌治疗等变量。评估腰椎侧弯的患病率，并在两组之间进行比较。还研究了腰椎侧弯与这些变量之间的关系。
在我们的652例乳腺癌患者中，有16例存在腰椎侧弯。对照组（7/316）和实验组（9/336）之间腰椎侧弯的患病率没有差异（p = 0.70）。根据逻辑回归分析，腰椎侧弯与手术、化疗、激素治疗、BMI和BMD没有显著关联（p>0.05）。然而，年龄与腰椎侧弯的患病率显示出显著关系（p<0.001；优势比，1.11；95%置信区间，1.054 - 1.170）。
乳腺癌患者腰椎侧弯的患病率为2.45%。腰椎侧弯与乳腺癌治疗、BMD和BMI无关。年龄是与腰椎侧弯患病率相关的唯一因素。
