Chatzidou Sofia, Repasos Evangelos, Plastiras Sotiris, Kontogiannis Christos, Kosmopoulos Marinos, Tsilimigras Diamantis I, Paraskevaidis Ioannis, Rokas Stelios
Department of Clinical Therapeutics, "Alexandra" Hospital, University of Athens, Athens, Greece.
Metropolitan Hospital, Athens, Greece.
Ann Noninvasive Electrocardiol. 2018 Jul;23(4):e12518. doi: 10.1111/anec.12518. Epub 2017 Dec 5.
Early repolarization syndrome (ERS) was originally considered a normal variant with benign outcome. However, recent studies have demonstrated that it can be linked to a considerable risk of life-threatening arrhythmias and sudden cardiac death. We report a case with an extraordinary, extremely malignant clinical expression of ERS refractory to all antiarrhythmic drugs including quinidine. This case demonstrates real-time changes of dynamic electrocardiogram (ECG) preceding a polymorphic ventricular tachycardia (VT)-ventricular fibrillation (VF) and possible external factors triggering arrhythmia onset. Implantable cardioverter-defibrillator (ICD) function was terminated 6 months after implantation due to multiple-incessant electrical storm (ES). Catheter ablation was the definite treatment of this malignant entity.
早期复极综合征（ERS）最初被认为是一种预后良好的正常变异。然而，最近的研究表明，它可能与危及生命的心律失常和心源性猝死的相当大风险有关。我们报告一例具有ERS异常、极其恶性临床表型的病例，对包括奎尼丁在内的所有抗心律失常药物均无效。该病例展示了多形性室性心动过速（VT）-心室颤动（VF）发作前动态心电图（ECG）的实时变化以及可能触发心律失常发作的外部因素。植入式心律转复除颤器（ICD）功能在植入后6个月因多次无休止电风暴（ES）而终止。导管消融是治疗这种恶性疾病的确定性方法。
