Wang Chun, Ma Yuan, Zhao Xin, Sun Pei-Li, Zhang Ying-Ming, Huang Mao, Zhu Yan, Jin Shu-Xian
Department of Respiratory and Critical Care Medicine, Nanjing Chest Hospital, Nanjing 210029, China.
Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
J Thorac Dis. 2017 Sep;9(9):E815-E826. doi: 10.21037/jtd.2017.08.54.
Glomus tumors (GTs) of the trachea are very rare neoplasms that usually arise from the distal portion of the respiratory tree. The origin of these tumors is modified smooth muscle cells of glomus bodies. In this study, we describe two cases of GT of the trachea, as well as the histologic features of these tumors and their treatments. One tumor was diagnosed via bronchoscopic biopsy, and the other tumor was diagnosed via surgery. Clinical follow-up showed that the two patients are alive and well after 8 and 15 months post-treatment, respectively. We also review the literature regarding GTs and discuss the clinical presentation, histologic features, differential diagnosis, treatment and prognosis of these tumors.
气管球瘤(GTs)是非常罕见的肿瘤,通常起源于呼吸树的远端部分。这些肿瘤起源于球状体的改良平滑肌细胞。在本研究中,我们描述了两例气管球瘤病例,以及这些肿瘤的组织学特征及其治疗方法。一例肿瘤通过支气管镜活检确诊,另一例通过手术确诊。临床随访显示,两名患者在治疗后分别存活了8个月和15个月,情况良好。我们还回顾了关于气管球瘤的文献,并讨论了这些肿瘤的临床表现、组织学特征、鉴别诊断、治疗和预后。