减肥手术患者口服蔗糖铁复合物补铁的疗效。BARI-FER研究。
Response to oral sucrosomial iron supplementation in patients undergoing bariatric surgery. The BARI-FER study.
作者信息
Ciudin Andreea, Simó-Servat Olga, Balibrea Jose Maria, Vilallonga Ramon, Hernandez Cristina, Simó Rafael, Mesa Jordi
机构信息
Institut de Recerca Vall d'Hebron, Universitat Autònoma de Barcelona (VHIR-UAB), Barcelona, Spain; CIBER de Diabetes y Enfermedades Metabólicas Asociadas, Instituto de Salud Carlos III, Spain; Endocrinology and Nutrition Department, Vall d'Hebron University Hospital, Barcelona, Spain.
Institut de Recerca Vall d'Hebron, Universitat Autònoma de Barcelona (VHIR-UAB), Barcelona, Spain; CIBER de Diabetes y Enfermedades Metabólicas Asociadas, Instituto de Salud Carlos III, Spain; Endocrinology and Nutrition Department, Vall d'Hebron University Hospital, Barcelona, Spain.
出版信息
Endocrinol Diabetes Nutr (Engl Ed). 2018 Jan;65(1):17-20. doi: 10.1016/j.endinu.2017.10.007. Epub 2017 Dec 7.
BACKGROUND
Chronic intravenous iron administration is often required after bariatric surgery. Oral sucrosomial iron has a particular form of absorption and may represent an alternative treatment.
OBJECTIVE
To assess the effect of switching to oral sucrosomial iron in patients receiving intravenous iron supplementation after bariatric surgery.
PATIENTS AND METHODS
A case-control study was conducted on 40 women of childbearing age, of whom 20 were switched to oral sucrosomial iron, while 20 patients continued on intravenous iron sucrose every three months.
RESULTS
No significant differences were seen in Hb, ferritin, and TSI levels before and after three months of treatment with sucrosomial iron.
CONCLUSION
Oral sucrosomial iron could be an alternative in patients who require parenteral treatment with iron after bariatric surgery.
背景
减肥手术后通常需要长期静脉注射铁剂。口服蔗糖铁具有特殊的吸收形式，可能是一种替代治疗方法。
目的
评估减肥手术后接受静脉补铁的患者改用口服蔗糖铁的效果。
患者和方法
对40名育龄女性进行了一项病例对照研究，其中20名改用口服蔗糖铁，而20名患者每三个月继续静脉注射蔗糖铁。
结果
使用蔗糖铁治疗三个月前后，血红蛋白、铁蛋白和总铁结合力水平均无显著差异。
结论
对于减肥手术后需要胃肠外补铁治疗的患者，口服蔗糖铁可能是一种替代方法。
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