1880年至2017年的遗传性痉挛性截瘫：历史回顾

Hereditary spastic paraplegia from 1880 to 2017: an historical review.

作者信息

Faber Ingrid, Pereira Eduardo Rafael, Martinez Alberto R M, França Marcondes, Teive Hélio Afonso Ghizoni

机构信息

Universidade Estadual de Campinas, Faculdade de Ciências Médicas, Departamento de Neurologia, Campinas SP, Brasil.

Universidade Federal do Paraná, Hospital de Clínicas, Departamento de Medicina Interna, Serviço de Neurologia, Setor de Distúrbios do Movimento, Curitiba PR, Brasil.

出版信息

Arq Neuropsiquiatr. 2017 Nov;75(11):813-818. doi: 10.1590/0004-282X20170160.

DOI:10.1590/0004-282X20170160

PMID:29236826

Abstract

The authors have constructed a brief timeline of major clinical research related to hereditary spastic paraplegia (HSP). This timeline summarizes the evolution of HSP research, from the first clinical descriptions by Adolf von Strümpell in 1880 to the present day, with the transformation of these diseases into a rapidly-growing and heterogeneous group of neurogenetic diseases.

摘要

作者构建了一份与遗传性痉挛性截瘫（HSP）相关的主要临床研究简要时间表。该时间表总结了HSP研究的发展历程，从1880年阿道夫·冯·施特吕姆佩尔首次进行临床描述至今，这些疾病已转变为一组快速增长且异质性的神经遗传性疾病。