Siu Stanley Py, Leung Wilson Kc, Wan Polly Sc, Liu Eric Kh, Lai Christopher Wk
1 Department of Health Technology and Informatics, the Hong Kong Polytechnic University, Hung Hom, Hong Kong.
2 Department of Imaging and Interventional Radiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong.
J Int Med Res. 2017 Dec;45(6):1930-1938. doi: 10.1177/0300060516688407. Epub 2017 Mar 16.
Objective To investigate the potential correlation between sonographically measured mesenteric fat thickness (MFT) and brachial artery flow-mediated dilation (FMD) in a sample of healthy Chinese male young adults. Methods Healthy male participants were recruited from Hong Kong Polytechnic University for this prospective observational study. The physical activity readiness questionnaire and ultrasound measurements of carotid intima media thickness were used to screen for clinically healthy subjects. MFT and brachial artery FMD were measured by ultrasound, and body mass index (BMI) was recorded. Results A total of 34 healthy male subjects, aged 19-26 years (mean ± SD BMI, 21.7 ± 3.2 kg/m) were included. Pearson's correlation coefficient test showed that brachial artery FMD had a statistically significant inverse relationship with BMI and with Log (MFT). Further stepwise multiple linear regression analysis showed that Log (MFT), and not BMI, was an independent predictor of impaired brachial artery FMD. Conclusions Sonographic measurements of MFT were an independent predictor of brachial artery FMD in Chinese male young adults.
目的 探讨在中国健康青年男性样本中,超声测量的肠系膜脂肪厚度(MFT)与肱动脉血流介导的扩张(FMD)之间的潜在相关性。方法 从香港理工大学招募健康男性参与者进行这项前瞻性观察性研究。使用身体活动准备情况问卷和颈动脉内膜中层厚度的超声测量来筛选临床健康的受试者。通过超声测量MFT和肱动脉FMD,并记录体重指数(BMI)。结果 共纳入34名年龄在19至26岁之间的健康男性受试者(平均±标准差BMI,21.7±3.2kg/m²)。Pearson相关系数检验显示,肱动脉FMD与BMI以及Log(MFT)存在统计学上显著的负相关关系。进一步的逐步多元线性回归分析表明,Log(MFT)而非BMI是肱动脉FMD受损的独立预测因素。结论 超声测量的MFT是中国青年男性肱动脉FMD的独立预测因素。