Ho Cheng-Yu, Seow Kok-Min, Huang Lee-Wen, Tsai Yieh-Loong
Department of Obstetrics & Gynecology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.
Department of Obstetrics & Gynecology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan; Department of Obstetrics and Gynecology, National Yang-Ming University, Taipei, Taiwan.
Taiwan J Obstet Gynecol. 2017 Dec;56(6):831-835. doi: 10.1016/j.tjog.2017.10.023.
Acquired uterine arteriovenous malformation (UAVM) is a rare, life-threatening disease. Angiography with uterine arterial embolization (UAE) is the diagnostic tool and a choice of fertility-sparing treatment. Here, we present a series of five successful pregnancies after embolization of UAVM.
Three reproductive aged women were treated for UAVM, resulting in five successful pregnancies. Their past history suggested that three cases had had previous uterine procedures, including second trimester abortion and elective dilatation and curettage. Intermittent heavy vaginal bleeding was the primary symptom of UAVM. One patient with anemia had two ineffective embolizations and achieved a singleton pregnancy after the third embolization. However, intrauterine fetal demise with severe fetal growth retardation was noted on the 28th gestation week. The other two women had temporary ovulation disorder after UAE. After Clomiphene Citrate (CC) treatment, successful pregnancies were achieved and carried to term uneventfully.
UAE is an acceptable method for preserving fertility and treatment in women with symptomatic UAVMs.
获得性子宫动静脉畸形(UAVM)是一种罕见的、危及生命的疾病。子宫动脉栓塞术(UAE)血管造影是诊断工具,也是一种保留生育功能的治疗选择。在此,我们报告了一系列5例UAVM栓塞术后成功妊娠的病例。
3名育龄期女性接受了UAVM治疗,最终成功妊娠5次。她们的既往史显示,其中3例曾接受过子宫手术,包括中期引产和选择性刮宫术。间歇性大量阴道出血是UAVM的主要症状。1例贫血患者接受了2次无效栓塞,第3次栓塞后成功单胎妊娠。然而,在妊娠第28周时发现宫内胎儿死亡伴严重胎儿生长受限。另外2名女性在UAE后出现暂时性排卵障碍。经枸橼酸氯米芬(CC)治疗后,成功妊娠并顺利足月分娩。
UAE是有症状的UAVM女性保留生育功能和治疗的一种可接受的方法。