Institut Pasteur, Microenvironment and Immunity Unit, 75724 Paris, France.
INSERM U1224, 75724 Paris, France.
Sci Immunol. 2017 Dec 15;2(18). doi: 10.1126/sciimmunol.aar2465.
Goblet cells deliver microbial antigens to generate regulatory T cells before and during weaning to induce long-term tolerance to symbionts.
杯状细胞在断奶前和期间将微生物抗原递呈给调节性 T 细胞,以诱导对共生体的长期耐受。