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拉各斯青少年的肠易激综合征

Irritable bowel syndrome in adolescents in Lagos.

作者信息

Adeniyi Oluwafunmilayo Funke, Adenike Lesi Olufunmilayo, Olatona Foluke Adenike, Esezobor Christoper Imokhuede, Ikobah Joanah Moses

机构信息

Department of Paediatrics, College of Medicine, University of Lagos,Lagos University Teaching Hospital, Idi-Araba, Lagos, Nigeria.

Department of Medicine, College of Medicine, University of Lagos, Lagos University Teaching Hospital, Idi-Araba, Lagos, Nigeria.

出版信息

Pan Afr Med J. 2017 Sep 29;28:93. doi: 10.11604/pamj.2017.28.93.11512. eCollection 2017.

Abstract

INTRODUCTION

irritable bowel syndrome (IBS) is one of the functional gastrointestinal disorders (FGIDs) which has been well described in western populations especially as the commonest cause of recurrent abdominal pain The aim of this study was to document the prevalence of Irritable bowel syndrome (IBS) amongst children in western Nigeria and increase the aware ness of IBS amongst physicians who manage children with abdominal pain.

METHODS

This was a cross-sectional study conducted amongst children aged 10-18 years in 8 schools located in two local government areas of Lagos state. A multistage stratified random-sampling survey was conducted using the validated Rome III criteria to assess for IBS and associated risk factors. The subtypes of IBS and associated extra-intestinal symptoms were also documented.

RESULTS

The prevalence of IBS was 16.0% in the study participants and the prevalence decreased with increasing age (p=0.05). Sixty two (62.5%) of the students with recurrent abdominal pain had IBS. IBS was more prevalent in the females compared to the males (p=0.000). The significant risk factors for IBS identified were gender (p=0.000), socioeconomic status (p=0.001) and past history of gastroenteritis (p=0.011). The commonest subtype of IBS seen was the alternating subtype.

CONCLUSION

IBS is prevalent in African children. Physicians who attend to children need to have a high index of suspicion for IBS in children who present with abdominal pain when there are no alarm symptoms. The need for further longitudinal studies in African children cannot be overemphasized.

摘要

引言

肠易激综合征(IBS)是功能性胃肠疾病(FGIDs)之一,在西方人群中已有详尽描述,尤其是作为复发性腹痛最常见的病因。本研究旨在记录尼日利亚西部儿童中肠易激综合征(IBS)的患病率,并提高诊治腹痛儿童的医生对IBS的认识。

方法

这是一项横断面研究,在拉各斯州两个地方政府辖区的8所学校中10至18岁的儿童中进行。采用经过验证的罗马III标准进行多阶段分层随机抽样调查,以评估IBS及相关危险因素。还记录了IBS的亚型及相关肠外症状。

结果

研究参与者中IBS的患病率为16.0%,患病率随年龄增长而降低(p=0.05)。62名(62.5%)复发性腹痛的学生患有IBS。女性IBS的患病率高于男性(p=0.000)。确定的IBS的重要危险因素为性别(p=0.000)、社会经济地位(p=0.001)和既往胃肠炎病史(p=0.011)。最常见的IBS亚型是交替型。

结论

IBS在非洲儿童中很普遍。诊治儿童的医生在面对无警示症状但出现腹痛的儿童时,需要对IBS有高度的怀疑指数。对非洲儿童进行进一步纵向研究的必要性再怎么强调也不为过。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e11/5724937/0acfc03489fe/PAMJ-28-93-g001.jpg

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