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男男性行为者在线样本中的性风险行为与艾滋病病毒照护连续过程

Sexual risk taking and the HIV care continuum in an online sample of men who have sex with men.

作者信息

Yoon Irene S, Downing Martin J, Teran Richard, Chiasson Mary Ann, Houang Steven T, Parsons Jeffrey T, Hirshfield Sabina

机构信息

a Division of Research and Evaluation , Public Health Solutions , New York , NY , USA.

b The Center for HIV/AIDS Educational Studies & Training , Hunter College of the City University of New York , New York , NY , USA.

出版信息

AIDS Care. 2018 Jul;30(7):921-929. doi: 10.1080/09540121.2017.1417535. Epub 2017 Dec 19.

Abstract

Antiretroviral Therapy (ART) suppresses HIV replication, reducing the risk of transmission. However, many people living with HIV in the US are not virally suppressed even after diagnosis and initiating ART, and may become disengaged from care at each stage of the HIV care continuum (HCC). In the current study we assessed the sexual risk behaviors of MSM by HCC stage. US MSM who completed an online survey (N = 12,995) in 2015 were categorized into 6 HCC groups. Mean age was 39.2 and a majority identified as White (49.6%). At every stage of the HCC, we found higher proportions of individuals engaged in care compared to CDC estimates. A majority of the sample was HIV-positive and engaged in care, with 67.2% of HIV-positive participants reporting viral suppression with ART. Across HCC groups, participants reported high rates of past 6-month condomless anal sex (CAS) (79.2%-84.8%) and CAS with serodiscordant or unknown status partners (38.0%-84.1%). Notably, MSM with unknown HIV serostatus reported the highest proportion of CAS and serodiscordant CAS. HIV-positive MSM not on ART were more likely to report an STI diagnosis (p < .002) compared to those unaware of their HIV status or HIV negative. Moreover, young Black MSM were less likely to be on ART (p < .002) or virally suppressed (p < .002) compared to older White MSM. Our findings highlight potentially problematic sexual risk behaviors among MSM by level of HCC engagement, which can impede the preventive impact of ART. Online platforms provide an avenue to assess the progress of MSM along the HCC, as well as other subpopulations in need of appropriate behavioral interventions to decrease HIV incidence.

摘要

抗逆转录病毒疗法(ART)可抑制HIV复制,降低传播风险。然而,在美国,许多HIV感染者即使在诊断并开始接受ART治疗后,病毒仍未得到抑制,并且在HIV治疗连续体(HCC)的每个阶段都可能脱离治疗。在本研究中,我们按HCC阶段评估了男男性行为者(MSM)的性风险行为。2015年完成在线调查的美国MSM(N = 12,995)被分为6个HCC组。平均年龄为39.2岁,大多数人认定为白人(49.6%)。在HCC的每个阶段,我们发现参与治疗的个体比例高于疾病控制与预防中心(CDC)的估计。样本中的大多数为HIV阳性且参与了治疗,67.2%的HIV阳性参与者报告通过ART实现了病毒抑制。在各个HCC组中,参与者报告过去6个月无保护肛交(CAS)的比例很高(79.2%-84.8%),与血清学不一致或状况不明的伴侣发生无保护肛交的比例也很高(38.0%-84.1%)。值得注意的是,HIV血清学状况不明的MSM报告的无保护肛交和血清学不一致的无保护肛交比例最高。与未意识到自己HIV感染状况或HIV阴性的MSM相比,未接受ART治疗的HIV阳性MSM更有可能报告性传播感染(STI)诊断(p < 0.002)。此外,与年长的白人MSM相比,年轻的黑人MSM接受ART治疗(p < 0.002)或实现病毒抑制(p < 0.002)的可能性较小。我们的研究结果突出了不同HCC参与水平的MSM中潜在存在问题的性风险行为,这可能会阻碍ART的预防效果。在线平台为评估MSM在HCC中的进展以及其他需要适当行为干预以降低HIV发病率的亚人群提供了一条途径。

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本文引用的文献

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HIV Care Outcomes Among Men Who Have Sex With Men With Diagnosed HIV Infection - United States, 2015.
MMWR Morb Mortal Wkly Rep. 2017 Sep 22;66(37):969-974. doi: 10.15585/mmwr.mm6637a2.
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Diminishing Perceived Threat of AIDS and Increasing Sexual Risks of HIV Among Men Who Have Sex with Men, 1997-2015.
Arch Sex Behav. 2017 May;46(4):895-902. doi: 10.1007/s10508-016-0934-9. Epub 2017 Feb 6.
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Antiretroviral Therapy for the Prevention of HIV-1 Transmission.
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