日本一例成人发作性周期性发热、口疮性口炎、咽炎和腺炎综合征病例。
A case of adult-onset periodic fever, aphthous stomatitis, pharyngitis, and adenitis syndrome in Japan.
作者信息
Yasuura Shusuke, Harada Yukinori
机构信息
Department of Internal Medicine Nagano Chuo Hospital Nagano Japan.
出版信息
J Gen Fam Med. 2017 May 2;18(5):261-264. doi: 10.1002/jgf2.51. eCollection 2017 Oct.
Abstract
Adult-onset periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome is rare. We report the case of a 23-year-old woman with PFAPA syndrome in Japan. Her symptoms lasted for approximately 5 days in each period regardless of nonsteroidal anti-inflammatory drug or antibiotic treatment. She was diagnosed with PFAPA syndrome based on her periodic self-limiting symptoms and no evidence of other febrile diseases. Following cimetidine therapy, her periodic symptoms diminished. PFAPA syndrome should be considered in patients presenting with periodic fever and upper respiratory symptoms regardless of their age or ethnicity.
摘要
成人发作性周期性发热、口疮性口炎、咽炎和腺炎（PFAPA）综合征较为罕见。我们报告了一名日本23岁患有PFAPA综合征的女性病例。无论使用非甾体抗炎药或抗生素治疗，她每个周期的症状都会持续约5天。根据她周期性的自限性症状且无其他发热性疾病的证据，她被诊断为PFAPA综合征。在接受西咪替丁治疗后，她的周期性症状有所减轻。对于出现周期性发热和上呼吸道症状的患者，无论其年龄或种族如何，都应考虑PFAPA综合征。
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