Irace L, Ben Hamida J, Martinelli O, Stumpo R, Irace F G, Venosi S, Gattuso R, Berloco P B, Gossetti B
G Chir. 2017 Sep-Oct;38(5):219-224. doi: 10.11138/gchir/2017.38.5.219.
The purpose of this paper is to evaluate the mid and long terms outcomes of open and endovascular surgical treatment, as well as multilayer stent, in patients affected by Renal Artery Aneurysm (RAA).
Twenty five patients with RAA (24 monolateral and 1 bilateral aneurysm, 26 aneurysms) were observed between 2000 and 2015: 4 were not treated due to the small size of the aneurysm (< 2.5 cm); out of the remaining, 16 underwent endovascular treatment, 2 were treated by open surgery consisting in aneurysmectomy and graft reconstruction and 5 (in 1 patient bilateral) were treated by ex vivo repair and autotransplantation.
Out of the 22 patients treated for RAA, one patient operated upon open surgery presented an early thrombosis of a PTFE graft, followed by nephrectomy (4.7%); one patient underwent autotransplantation showed an ureteral kinking without functional consequences. In a follow-up ranging from 1 and 11 years (mean 5 years), no deaths were observed; all the renal arteries repaired were patents and 16 out of 21 patients had a significative reduction of systemic blood pressure.
The choice of the best treatment is based on aneurysm's morphology according to Rundback's classification. The type I, involving the main renal artery, is always treated by endovascular approach; type II, involving renal artery bifurcations may be treated by open surgery or multilayer stents; type III (hilar or intraparenchymal aneurysms) needs only an open surgical treatment as autotransplantation.
Based on our experience it seems that most of RAAs may be treated by endovascular technique. The ex vivo autotransplantation represents the first-line treatment in hilar and intraparenchymal aneurysms. Multilayer stents seem to have good outcome in the treatment of aneurysms involving arterial bifurcations. Mid and long term results, related to kidney preservation and to normalization of blood pressure, seems satisfying.
本文旨在评估开放性手术、血管腔内手术治疗以及多层支架治疗肾动脉动脉瘤(RAA)患者的中长期疗效。
2000年至2015年间观察了25例RAA患者(24例单侧动脉瘤和1例双侧动脉瘤,共26个动脉瘤):4例因动脉瘤较小(<2.5 cm)未接受治疗;其余患者中,16例行血管腔内治疗,2例行开放性手术,包括动脉瘤切除术和移植物重建,5例(其中1例为双侧)行离体修复和自体移植。
在22例接受RAA治疗的患者中,1例行开放性手术的患者出现聚四氟乙烯移植物早期血栓形成,随后行肾切除术(4.7%);1例行自体移植的患者出现输尿管扭结,但未产生功能影响。在1至11年(平均5年)的随访中,未观察到死亡病例;所有修复的肾动脉均通畅,21例患者中有16例全身血压显著降低。
根据Rundback分类,最佳治疗方法的选择基于动脉瘤的形态。I型,累及肾主动脉,始终采用血管腔内方法治疗;II型,累及肾动脉分叉,可采用开放性手术或多层支架治疗;III型(肾门或实质内动脉瘤)仅需行开放性手术,如自体移植。
根据我们的经验,大多数RAA似乎可通过血管腔内技术治疗。离体自体移植是肾门和实质内动脉瘤的一线治疗方法。多层支架在治疗累及动脉分叉的动脉瘤方面似乎有良好疗效。与肾脏保留和血压正常化相关的中长期结果似乎令人满意。