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在接受泌尿生殖系统手术的儿科患者中,尾侧地塞米松与静脉用地塞米松作为尾侧阻滞辅助用药的镇痛效果比较。

Comparison of Analgesic Efficacy of Caudal Dexamethasone with Intravenous Dexamethasone as an Adjuvant to Caudal Block in Pediatric Patients Undergoing Urogenital Surgeries.

作者信息

Dongare Dhanashree H, Karhade Seema S

机构信息

Department of Anaesthesia, Smt. Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India.

出版信息

Anesth Essays Res. 2017 Oct-Dec;11(4):1009-1012. doi: 10.4103/aer.AER_143_17.

Abstract

CONTEXT

Caudal block is one of the most common regional anesthetic techniques employed in pediatric urogenital surgeries. Adjuvants play an important role to improve postoperative analgesia.

AIMS

The aim of this study was to evaluate the analgesic effect of dexamethasone when given systemically as against caudally as an adjuvant to caudal block.

SUBJECTS AND METHODS

In this randomized controlled study, sixty American Society of Anesthesiologists Physical Status I and II patients aged 3-6 years were randomly allocated into two groups of thirty each. Group D received caudal block with local anesthetic solution and 0.1 mg/kg injection dexamethasone. Group I received a caudal block with local anesthetic solution. They received intravenous injection dexamethasone 0.1 mg/kg after the block. Both the groups were compared for the duration of postoperative analgesia and analgesic requirement.

STATISTICAL ANALYSIS USED

Statistical analysis was done with unpaired -test and Chi-square test as was appropriate.

RESULTS

Group D showed a significant prolongation of postoperative analgesia (626.33 ± 59.39 min) as compared to Group I (194.67 ± 27.76 min). Similarly, requirement of analgesic was reduced on 1 postoperative day in group receiving caudal dexamethasone.

CONCLUSIONS

Dexamethasone significantly prolongs the duration of postoperative analgesia of a caudal block when given caudally than when given intravenously.

摘要

背景

骶管阻滞是小儿泌尿生殖系统手术中最常用的区域麻醉技术之一。辅助药物在改善术后镇痛方面发挥着重要作用。

目的

本研究旨在评估地塞米松经骶管给药与经静脉给药作为骶管阻滞辅助药物时的镇痛效果。

对象与方法

在这项随机对照研究中,60例年龄在3至6岁、美国麻醉医师协会身体状况分级为Ⅰ级和Ⅱ级的患者被随机分为两组,每组30例。D组接受局部麻醉药溶液加0.1mg/kg地塞米松注射的骶管阻滞。I组接受局部麻醉药溶液的骶管阻滞。阻滞完成后,两组均接受0.1mg/kg地塞米松静脉注射。比较两组的术后镇痛持续时间和镇痛需求。

所用统计分析方法

根据情况采用非配对t检验和卡方检验进行统计分析。

结果

与I组(194.67±27.76分钟)相比,D组术后镇痛时间显著延长(626.33±59.39分钟)。同样,接受骶管地塞米松的组在术后第1天镇痛需求减少。

结论

地塞米松经骶管给药比经静脉给药能显著延长骶管阻滞的术后镇痛时间。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d439/5735440/f6f5096d93af/AER-11-1009-g001.jpg

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