Ivarsson L, Nilsson N J, Lundgren O
Department of Physiology, University of Göteborg, Sweden.
Acta Physiol Scand. 1989 Mar;135(3):293-7. doi: 10.1111/j.1748-1716.1989.tb08580.x.
Venous appearance of oxygen and red cells labelled with methaemoglobin was compared in the gastric vascular bed. At 'resting' gastric blood flow the red cells appeared earlier than oxygen after simultaneous close i.a. injection, as would be expected from the intravascular laminar flow profile. However, when lowering arterial inflow pressure to the stomach by partially occluding the coeliac trunk, oxygen often appeared earlier than the red blood cells. When arterial pressure was lower than 50 mmHg this was always the case. This observation is taken to indicate that during these experimental conditions an extravascular shunting of oxygen occurs. It is suggested that this may occur in the submucosal vascular network and/or in the mucosa. The functional implications of such a mechanism are tentatively discussed.
在胃血管床中比较了用高铁血红蛋白标记的氧和红细胞的静脉表现。在“静息”胃血流状态下，同时经动脉内近距离注射后，红细胞比氧出现得更早，这正如血管内层流分布所预期的那样。然而，当通过部分阻断腹腔干来降低进入胃的动脉流入压时，氧常常比红细胞出现得更早。当动脉压低于50 mmHg时，情况总是如此。这一观察结果表明，在这些实验条件下发生了氧的血管外分流。有人提出，这可能发生在黏膜下血管网络和/或黏膜中。初步讨论了这种机制的功能意义。
