Kubricht V, Sevcik P
Bratisl Lek Listy. 2017;118(12):746-751. doi: 10.4149/BLL_2017_141.
To investigate the influence of an Acute Pain Service (APS) on the incidence of chronic postsurgical pain (CPSP). To assess the acute pain intensity as a risk factor for CPSP. The impact of an APS on the incidence of CPSP has not yet been studied.
Retrospective questionnaire given to randomized cohorts study, performed in two hospitals - Hospital A with an APS and Hospital B without such service. 1444 patients underwent eight different surgical procedures in both hospitals within one year, 175 patients from each hospital were randomized.
208 questionnaires were analysed. There was a significant difference in acute pain intensity in the first 24 hours after surgery. The difference of CPSP incidence between hospitals was not significant (Hospital A nine patients (8.6 %), Hospital B sixteen patients (15.5 %). The patients with CPSP experienced significantly more intensive pain in the first 24 hours and at discharge than patients without CPSP regardless of the hospital.
The study did not demonstrate the incidence of CPSP was lower in the hospital with an APS despite the lower postoperative pain scores. However there was a noticeable trend toward higher incidence of CPSP in the hospital without an APS. The study demonstrated that APS decreases intensity of an acute postoperative pain and acute pain intensity is a risk factor for CPSP incidence (Tab. 5, Ref. 27).
探讨急性疼痛服务(APS)对慢性术后疼痛(CPSP)发生率的影响。评估急性疼痛强度作为CPSP的一个危险因素。APS对CPSP发生率的影响尚未得到研究。
对在两家医院进行的随机队列研究采用回顾性问卷调查,医院A设有APS,医院B没有该服务。一年内两家医院共有1444例患者接受了8种不同的外科手术,每家医院随机抽取175例患者。
分析了208份问卷。术后24小时内急性疼痛强度存在显著差异。两家医院之间CPSP发生率的差异不显著(医院A有9例患者(8.6%),医院B有16例患者(15.5%)。无论在哪家医院,发生CPSP的患者在术后24小时及出院时经历的疼痛都比未发生CPSP的患者明显更强烈。
该研究未表明设有APS的医院中CPSP的发生率更低,尽管术后疼痛评分较低。然而,在没有APS的医院中,CPSP发生率有明显更高的趋势。该研究表明,APS可降低术后急性疼痛的强度,且急性疼痛强度是CPSP发生率的一个危险因素(表5,参考文献27)。