Lipira Lauren, Kemp Christopher, Domercant Jean Wysler, Honoré Jean Guy, Francois Kesner, Puttkammer Nancy
Department of Health Services, University of Washington, Seattle, WA, USA.
Department of Global Health, University of Washington, Seattle, WA, USA.
Int Health. 2018 Jan 1;10(1):54-62. doi: 10.1093/inthealth/ihx060.
Option B+ is a strategy wherein pregnant or breastfeeding women with HIV are enrolled in lifelong antiretroviral therapy (ART) for prevention of mother-to-child transmission (PMTCT) of HIV. In Haiti, attrition from Option B+ is problematic and variable across health care facilities. This study explores service readiness and other facility factors as predictors of Option B+ attrition in Haiti.
This analysis used longitudinal data from 2012 to 2014 from the iSanté electronic medical record system and cross-sectional data from Haiti's 2013 Service Provision Assessment. Predictors included Service Availability and Readiness Assessment (SARA) measures for antenatal care (ANC), PMTCT, HIV care services and ART services; general facility characteristics and patient-level factors. Multivariable Cox proportional hazards models modelled the time to first attrition.
Analysis of data from 3147 women at 63 health care facilities showed no significant relationships between SARA measures and attrition. Having integrated ANC/PMTCT care and HIV-related training were significant protective factors. Being a public-sector facility, having a greater number of quality improvement activities and training in ANC were significant risk factors.
Several facility-level factors were associated with Option B+ attrition. Future research is needed to explore unmeasured facility factors, clarify causal relationships, and incorporate community-level factors into the analysis of Option B+ attrition.
“方案B+”是一项策略,即让感染艾滋病毒的孕妇或哺乳期妇女接受终身抗逆转录病毒治疗(ART),以预防艾滋病毒母婴传播(PMTCT)。在海地,“方案B+”的人员流失问题严重,且在各医疗机构中存在差异。本研究探讨了服务准备情况及其他机构因素,作为海地“方案B+”人员流失的预测指标。
本分析使用了2012年至2014年来自iSanté电子病历系统的纵向数据,以及2013年海地服务提供评估的横断面数据。预测指标包括产前护理(ANC)、预防母婴传播、艾滋病毒护理服务和抗逆转录病毒治疗服务的服务可用性和准备情况评估(SARA)指标;一般机构特征和患者层面因素。多变量Cox比例风险模型对首次流失时间进行了建模。
对63家医疗机构的3147名妇女的数据进行分析后发现,SARA指标与人员流失之间无显著关系。提供综合的产前护理/预防母婴传播服务以及开展与艾滋病毒相关的培训是显著的保护因素。作为公共部门机构、开展更多质量改进活动以及进行产前护理培训是显著的风险因素。
若干机构层面因素与“方案B+”的人员流失有关。未来需要开展研究,以探索未测量的机构因素,阐明因果关系,并将社区层面因素纳入“方案B+”人员流失分析。