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ART Attrition across Health Facilities Implementing Option B+ in Haiti.海地实施B+方案的医疗机构中的抗逆转录病毒治疗减员情况。
J Int Assoc Provid AIDS Care. 2018 Jan-Dec;17:2325958218774037. doi: 10.1177/2325958218774037.
2
Attrition from antiretroviral treatment services among pregnant and non-pregnant patients following adoption of Option B+ in Haiti.海地采用B+方案后,孕妇和非孕妇抗逆转录病毒治疗服务的人员流失情况。
Glob Health Action. 2017;10(1):1330915. doi: 10.1080/16549716.2017.1330915.
3
ART attrition and risk factors among Option B+ patients in Haiti: A retrospective cohort study.海地接受B+方案治疗的患者中抗逆转录病毒治疗的中断情况及风险因素:一项回顾性队列研究。
PLoS One. 2017 Mar 6;12(3):e0173123. doi: 10.1371/journal.pone.0173123. eCollection 2017.
4
Supporting Option B+ scale up and strengthening the prevention of mother-to-child transmission cascade in central Malawi: results from a serial cross-sectional study.支持在马拉维中部扩大B+方案并加强母婴传播防治流程:一项系列横断面研究的结果
BMC Infect Dis. 2015 Aug 12;15:328. doi: 10.1186/s12879-015-1065-y.
5
A systematic review of health system barriers and enablers for antiretroviral therapy (ART) for HIV-infected pregnant and postpartum women.对感染艾滋病毒的孕妇和产后妇女抗逆转录病毒治疗(ART)的卫生系统障碍与促进因素的系统评价。
PLoS One. 2014 Oct 10;9(10):e108150. doi: 10.1371/journal.pone.0108150. eCollection 2014.
6
"What they wanted was to give birth; nothing else": barriers to retention in option B+ HIV care among postpartum women in South Africa.“她们想要的只是分娩;别的都不重要”:南非产后妇女在接受选项 B+HIV 护理时面临的保留障碍。
J Acquir Immune Defic Syndr. 2014 Sep 1;67(1):e12-8. doi: 10.1097/QAI.0000000000000263.
7
What does high and low have to do with it? Performance classification to identify health system factors associated with effective prevention of mother-to-child transmission of HIV delivery in Mozambique.这与高低有什么关系?进行绩效分类以确定莫桑比克与有效预防艾滋病母婴传播分娩相关的卫生系统因素。
J Int AIDS Soc. 2014 Mar 24;17(1):18828. doi: 10.7448/IAS.17.1.18828. eCollection 2014.
8
Retention in care under universal antiretroviral therapy for HIV-infected pregnant and breastfeeding women ('Option B+') in Malawi. Malawi 实施针对 HIV 感染孕妇和哺乳期妇女的普遍抗逆转录病毒治疗(“B+方案”)的患者保持治疗情况。
AIDS. 2014 Feb 20;28(4):589-598. doi: 10.1097/QAD.0000000000000143.
9
Integrating antiretroviral therapy into antenatal care and maternal and child health settings: a systematic review and meta-analysis.将抗逆转录病毒疗法整合到产前保健以及母婴健康保健服务中:系统评价和荟萃分析。
Bull World Health Organ. 2013 Jan 1;91(1):46-56. doi: 10.2471/BLT.12.107003. Epub 2012 Nov 28.
10
Attrition from HIV testing to antiretroviral therapy initiation among patients newly diagnosed with HIV in Haiti.海地新诊断出 HIV 的患者中,从 HIV 检测到开始抗逆转录病毒治疗的脱落率。
J Acquir Immune Defic Syndr. 2013 Mar 1;62(3):e61-9. doi: 10.1097/QAI.0b013e318281e772.

服务准备情况和医疗保健机构因素在海地B+方案人员流失中的作用:电子病历与服务提供评估调查数据的联合分析

The role of service readiness and health care facility factors in attrition from Option B+ in Haiti: a joint examination of electronic medical records and service provision assessment survey data.

作者信息

Lipira Lauren, Kemp Christopher, Domercant Jean Wysler, Honoré Jean Guy, Francois Kesner, Puttkammer Nancy

机构信息

Department of Health Services, University of Washington, Seattle, WA, USA.

Department of Global Health, University of Washington, Seattle, WA, USA.

出版信息

Int Health. 2018 Jan 1;10(1):54-62. doi: 10.1093/inthealth/ihx060.

DOI:10.1093/inthealth/ihx060
PMID:29329386
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6454494/
Abstract

BACKGROUND

Option B+ is a strategy wherein pregnant or breastfeeding women with HIV are enrolled in lifelong antiretroviral therapy (ART) for prevention of mother-to-child transmission (PMTCT) of HIV. In Haiti, attrition from Option B+ is problematic and variable across health care facilities. This study explores service readiness and other facility factors as predictors of Option B+ attrition in Haiti.

METHODS

This analysis used longitudinal data from 2012 to 2014 from the iSanté electronic medical record system and cross-sectional data from Haiti's 2013 Service Provision Assessment. Predictors included Service Availability and Readiness Assessment (SARA) measures for antenatal care (ANC), PMTCT, HIV care services and ART services; general facility characteristics and patient-level factors. Multivariable Cox proportional hazards models modelled the time to first attrition.

RESULTS

Analysis of data from 3147 women at 63 health care facilities showed no significant relationships between SARA measures and attrition. Having integrated ANC/PMTCT care and HIV-related training were significant protective factors. Being a public-sector facility, having a greater number of quality improvement activities and training in ANC were significant risk factors.

CONCLUSION

Several facility-level factors were associated with Option B+ attrition. Future research is needed to explore unmeasured facility factors, clarify causal relationships, and incorporate community-level factors into the analysis of Option B+ attrition.

摘要

背景

“方案B+”是一项策略,即让感染艾滋病毒的孕妇或哺乳期妇女接受终身抗逆转录病毒治疗(ART),以预防艾滋病毒母婴传播(PMTCT)。在海地,“方案B+”的人员流失问题严重,且在各医疗机构中存在差异。本研究探讨了服务准备情况及其他机构因素,作为海地“方案B+”人员流失的预测指标。

方法

本分析使用了2012年至2014年来自iSanté电子病历系统的纵向数据,以及2013年海地服务提供评估的横断面数据。预测指标包括产前护理(ANC)、预防母婴传播、艾滋病毒护理服务和抗逆转录病毒治疗服务的服务可用性和准备情况评估(SARA)指标;一般机构特征和患者层面因素。多变量Cox比例风险模型对首次流失时间进行了建模。

结果

对63家医疗机构的3147名妇女的数据进行分析后发现,SARA指标与人员流失之间无显著关系。提供综合的产前护理/预防母婴传播服务以及开展与艾滋病毒相关的培训是显著的保护因素。作为公共部门机构、开展更多质量改进活动以及进行产前护理培训是显著的风险因素。

结论

若干机构层面因素与“方案B+”的人员流失有关。未来需要开展研究,以探索未测量的机构因素,阐明因果关系,并将社区层面因素纳入“方案B+”人员流失分析。