Soler Lisa M, Raymond Steven L, Larson Shawn D, Taylor Janice A, Islam Saleem
Division of Pediatric Surgery, Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA.
Division of Pediatric Surgery, Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA.
J Pediatr Surg. 2018 Oct;53(10):1960-1963. doi: 10.1016/j.jpedsurg.2017.12.014. Epub 2017 Dec 27.
The management of primary spontaneous pneumothorax (PSP) in the pediatric population is not standardized. The purpose of this study was to understand the management options for a first episode of PSP in children and adolescents, and their associated outcomes.
A retrospective study was conducted for patients 5-20 years old with a diagnosis of PSP at a large academic children's hospital between 2002 and 2014. Patient data were reviewed for each case. Management and outcomes were analyzed and compared between groups.
Eighty patients met all inclusion criteria. Overall recurrence rate was 40% with 86% occurring within 12 months of the initial PSP. Patients with recurrent PSP were significantly taller. Size of pneumothorax based on initial chest x-ray was comparable between recurrent and nonrecurrent groups. A negative CT scan for subpleural blebs did not predict recurrence. Patients undergoing thoracoscopic blebectomy and mechanical pleurodesis at initial presentation had significantly lower recurrence rate compared to patients who underwent nonoperative management (operative group 14%, nonoperative group 45%; p=0.0373).
Recurrence following nonoperative management was high with the majority occurring within a year and requiring readmission. These findings support offering surgery to families as a potential initial management option.
3b/4 - retrospective series or case control study, single institution, very limited population.
小儿原发性自发性气胸(PSP)的治疗尚无标准化方案。本研究旨在了解儿童和青少年首次发作PSP的治疗选择及其相关结局。
对2002年至2014年期间在一家大型学术儿童医院诊断为PSP的5至20岁患者进行回顾性研究。对每个病例的患者数据进行回顾。分析并比较各组的治疗方法和结局。
80例患者符合所有纳入标准。总体复发率为40%,其中86%发生在初次PSP后的12个月内。复发性PSP患者明显更高。根据初次胸部X线检查结果,复发性和非复发性气胸组的气胸大小相当。CT扫描未发现胸膜下肺大疱并不能预测复发。与接受非手术治疗的患者相比,初次就诊时接受胸腔镜肺大疱切除术和机械胸膜固定术的患者复发率显著降低(手术组为14%,非手术组为45%;p = 0.0373)。
非手术治疗后的复发率很高,大多数复发发生在一年内且需要再次入院。这些发现支持将手术作为一种潜在的初始治疗选择提供给患者家属。
3b/4 - 回顾性系列研究或病例对照研究,单机构,研究人群非常有限。