Sudo Yuna, Takagawa Ryo, Kohagura Kaori, Hashimoto Itaru, Yokoi Hideto, Sugawara Yuko, Arisaka Hayaka, Segami Kenki, Hayashi Tsutomu, Shimada Kazuhiro, Murakami Hitoshi, Hirakawa Shohei, Hasegawa Seiji, Fukushima Tadao, Ike Hideyuki, Imada Toshio
Dept. of Surgery, Saiseikai Yokohama City Nanbu Hospital.
Gan To Kagaku Ryoho. 2018 Jan;45(1):85-87.
An 84-year-old man visited our hospital with epigastralgia.Levels of hepatic and biliary enzymes and CRP were elevated, as detected by a blood test.On a CT scan, a swollen gallbladder with stones was detected.The patient was admitted to the hospital with a diagnosis of Grade I acute cholecystitis.Conservative treatment was continued with antibiotic administration and the patient was discharged from the hospital with improvement on day 6 after admission.Three months later, the patient underwent laparoscopic cholecystectomy.In the gallbladder, a 45×45 mm tumor was found.Upon pathological examination, diffuse proliferation of lymphocyte-like heterotypic cells and subserosal invasion were observed.Immunohistochemistry results were negative for MUM1 and positive for CD10 and Bcl6 markers.A malignant diffuse large B-cell lymphoma was diagnosed.We experienced a case of malignant lymphoma of the gallbladder diagnosed after surgery for acute cholecystitis, which we herein report with literature consideration.