Department of Thoracic and Cardiovascular Surgery, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Gyeongsangnam-do, South Korea.
Department of Pediatrics, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Gyeongsangnam-do, South Korea.
Eur J Cardiothorac Surg. 2018 Jun 1;53(6):1223-1229. doi: 10.1093/ejcts/ezx497.
We adopted an operative technique of pulmonary valve (PV) annular enlargement with valve repair in tetralogy of Fallot (TOF) correction to reduce postoperative pulmonary regurgitation (PR) 16 years ago. Here, we have evaluated the long-term results.
Between April 2000 and August 2005, 43 patients (26 men) with tetralogy of Fallot with pulmonary stenosis underwent PV annular enlargement with valve repair. The median age and body weight at the time of surgery were 14 months and 10.2 kg, respectively.
There was no operative mortality. Mean postoperative PR grade at discharge was 0.93 ± 0.40 (none or trivial in 10 patients, mild in 27 patients, mild to moderate in 5 patients and moderate in 1 patient), and the mean postoperative pressure gradient across PV was 13.0 ± 10.9 mmHg. The mean follow-up duration was 131.9 ± 42.9 months. During follow-up, 1 reoperation was performed for residual ventricular septal defect. The mean PR grade at the last follow-up echocardiography was 1.59 ± 0.60 (mild in 17 patients, mild to moderate in 8 patients, moderate in 14 patients, moderate to severe in 1 patient and severe in 3 patients), and the mean pressure gradient was 22.7 ± 9.9 mmHg. We have compared the incidence of moderate or more PR with the incidence of patients who underwent simple transannular patch enlargement through propensity score matching. The PV repair group had a lower incidence of moderate or more PR compared with the simple transannular patch group (40% vs 68%, P = 0.04).
PV annular enlargement with valve repair has reasonable long-term results and yields a lower long-term incidence of significant PR compared with the simple transannular patch enlargement technique.
16 年前,我们采用肺动脉瓣(PV)瓣环扩大联合瓣叶修复技术治疗法洛四联症(TOF)矫正术后肺动脉瓣反流(PR)。本研究旨在评估其长期结果。
2000 年 4 月至 2005 年 8 月,43 例(男 26 例)法洛四联症合并肺动脉瓣狭窄患者接受了 PV 瓣环扩大联合瓣叶修复手术。手术时的中位年龄和体重分别为 14 个月和 10.2kg。
无手术死亡。出院时平均术后 PR 分级为 0.93±0.40(10 例为无或轻度,27 例为轻度至中度,5 例为轻度至中度,1 例为中度),平均术后 PV 跨瓣压差为 13.0±10.9mmHg。中位随访时间为 131.9±42.9 个月。随访期间,1 例因残余室间隔缺损再次手术。最后一次超声心动图检查的平均 PR 分级为 1.59±0.60(17 例为轻度,8 例为轻度至中度,14 例为中度,1 例为中度至重度,3 例为重度),平均压差为 22.7±9.9mmHg。我们通过倾向评分匹配比较了中度或更严重 PR 的发生率和单纯瓣环成形术组的发生率。与单纯瓣环成形术组相比,PV 修复组中度或更严重 PR 的发生率较低(40% vs 68%,P=0.04)。
与单纯瓣环成形术相比,PV 瓣环扩大联合瓣叶修复术具有合理的长期效果,且长期发生严重 PR 的发生率较低。