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[念珠菌粪石或真菌球导致的尿路梗阻]

[Urinary tract obstruction by Candida bezoars, or fungus balls].

作者信息

Domart Y, Delmas V, Cornud F, Bouchama A, Chastre J, Gibert C

出版信息

Presse Med. 1986 Feb 1;15(4):153-6.

PMID:2938118
Abstract

Two patients admitted to an intensive care unit for severe bacterial infection develops Candida albicans superinfection with obstruction of the urinary canals by "fungus balls". The development of medico-surgical techniques using antibiotics and immunosuppressive drugs accounts for the increasing incidence of disseminated candidiasis. The kidneys are particularly sensitive to Candida infections. Fungus balls are conglomerates of mycelium which may result in obstruction of the urinary tract. Their clinical, radiological and ultrasonic features, as well as the microbiological and serological diagnostic problems they raise are described. Ultrasonically guided percutaneous nephrostomy is a very interesting technique for the diagnosis of the condition and its local treatment by drainage and lavage with amphotericin B. This antifungal, combined with flucytosine is still used for the systemic treatment of candidiasis.

摘要

两名因严重细菌感染入住重症监护病房的患者发生白色念珠菌二重感染,出现“真菌球”阻塞尿道的情况。使用抗生素和免疫抑制药物的医疗手术技术的发展导致播散性念珠菌病的发病率不断上升。肾脏对念珠菌感染尤为敏感。真菌球是菌丝体的聚集体,可能导致尿路梗阻。文中描述了它们的临床、放射学和超声特征,以及它们引发的微生物学和血清学诊断问题。超声引导下经皮肾造瘘术是一种非常有趣的技术,可用于该病的诊断及其通过引流和两性霉素B灌洗进行局部治疗。这种抗真菌药物与氟胞嘧啶联合仍用于念珠菌病的全身治疗。

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