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巨大骶尾部畸胎瘤中发生的黏液性肿瘤:一例罕见病例报告。

Mucinous tumor arising in a giant sacrococcygeal teratoma: A rare case report.

作者信息

Zhang Fengtian, Yu Xiaolong, Zeng Jin, Dai Min

机构信息

Department of Orthopedics, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, Nanchang, Jiangxi, China.

出版信息

Medicine (Baltimore). 2017 Nov;96(47):e8759. doi: 10.1097/MD.0000000000008759.

DOI:10.1097/MD.0000000000008759
PMID:29381973
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5708972/
Abstract

RATIONALE

Teratomas, which most frequently affect adult females, are the most common type of germ cell tumor, it always comprises derivatives of at least 2 germ layers. The most common site of primary teratomas is the ovary. Sacrococcygeal teratomas (SCTs), which are exceedingly rare in adults, are generally found in newborns or children.

PATIENT CONCERNS

A 39-year-old woman presented to our clinic with a 1-year history of gradually aggravated difficulty in micturition and defecation, and a tumor in her right buttock present since birth. Appropriate preoperative examinations showed a large (15.6 cm × 12.2 cm × 30.0 cm) multicystic SCT.

DIAGNOSES

Histologic examination confirmed a mucinous tumor arising in a giant SCT.

INTERVENTIONS

Abdominoperineal rectal resection was performed.

OUTCOMES

The patient recovered well and was discharged on day 33 of admission.

LESSONS

We report the first case of a mucinous tumor arising in an SCT, in which the teratoma presented mature tissue elements derived only from the endodermal germ layer (keratinous debris).

摘要

原理

畸胎瘤是最常见的生殖细胞肿瘤类型,最常发生于成年女性,总是包含至少两个胚层的衍生物。原发性畸胎瘤最常见的部位是卵巢。骶尾部畸胎瘤(SCT)在成年人中极为罕见,通常见于新生儿或儿童。

患者情况

一名39岁女性因排尿和排便困难逐渐加重1年,且自出生以来右臀部有一肿瘤,前来我院就诊。适当的术前检查显示为一个巨大的(15.6厘米×12.2厘米×30.0厘米)多囊性骶尾部畸胎瘤。

诊断

组织学检查证实为巨大骶尾部畸胎瘤内发生的黏液性肿瘤。

干预措施

行腹会阴直肠切除术。

结果

患者恢复良好,入院第33天出院。

经验教训

我们报告了首例骶尾部畸胎瘤内发生的黏液性肿瘤病例,该畸胎瘤呈现仅来自内胚层生殖层(角质碎屑)的成熟组织成分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a7d/5708972/a2b663c8eb94/medi-96-e8759-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a7d/5708972/aca6e9df2f0e/medi-96-e8759-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a7d/5708972/e2e79b52ea6e/medi-96-e8759-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a7d/5708972/ac46a95e035a/medi-96-e8759-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a7d/5708972/a2b663c8eb94/medi-96-e8759-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a7d/5708972/aca6e9df2f0e/medi-96-e8759-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a7d/5708972/e2e79b52ea6e/medi-96-e8759-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a7d/5708972/ac46a95e035a/medi-96-e8759-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a7d/5708972/a2b663c8eb94/medi-96-e8759-g004.jpg

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J Obstet Gynaecol Res. 2017 Apr;43(4):744-748. doi: 10.1111/jog.13271. Epub 2017 Mar 28.
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Identical twins with mature cystic teratomas treated with laparoscopic surgery: Two case reports.腹腔镜手术治疗成熟囊性畸胎瘤的同卵双胞胎:两例报告。
Mol Clin Oncol. 2017 Feb;6(2):276-278. doi: 10.3892/mco.2016.1118. Epub 2016 Dec 28.
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Sebaceous adenoma arising in mature cystic teratoma of the ovary. Case report.
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Cesk Patol. 2017 Winter;53(1):35-37.
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Mature Cystic Teratoma with Co-existent Mucinous Cystadenocarcinoma in the same Ovary-A Diagnostic Dilemma.同一卵巢内成熟性囊性畸胎瘤合并黏液性囊腺癌——诊断难题
J Clin Diagn Res. 2016 Dec;10(12):ED11-ED13. doi: 10.7860/JCDR/2016/22150.9118. Epub 2016 Dec 1.
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