口腔鳞状细胞癌的神经周围浸润：外科医生面临的新障碍。
Perineural Invasion of Oral Squamous Cell Carcinoma: A New Hurdle for Surgeons.
作者信息
Keerthi R, Dutta Abhishek, Agarwal Shruthi, Kani Vikram, Khatua Abhishek
机构信息
Department of Oral and Maxillofacial Surgery, V.S. Dental College and Hospital, Bangalore, India.
出版信息
J Maxillofac Oral Surg. 2018 Mar;17(1):59-63. doi: 10.1007/s12663-016-0943-1. Epub 2016 Jul 15.
Abstract
The high rate of mortality associated with cancer is due to its inherent nature to metastasize. Perineural invasion (PNI) is a relatively rare mode of metastasis, and a distinct pathologic entity that can be observed in the absence of lymphatic or vascular invasion which is still shrouded by mystery. PNI is a marker of poor prognosis. Despite increasing recognition of this metastatic process, there has been little progress in the understanding of mechanisms behind PNI. The purpose of this article is to make surgeons aware of caudad to cephalad metastasis of oral cancer along trigeminal nerve.
摘要
与癌症相关的高死亡率归因于其固有的转移特性。神经周围侵犯（PNI）是一种相对罕见的转移方式，是一种独特的病理实体，可在无淋巴管或血管侵犯的情况下观察到，其机制仍不明朗。PNI是预后不良的一个标志。尽管对这一转移过程的认识不断增加，但在理解PNI背后的机制方面进展甚微。本文旨在让外科医生了解口腔癌沿三叉神经从尾端向头端转移的情况。
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