两名患者因汗腺功能和结构异常出现手部局限性多汗症。
Two patients with localised hyperhidrosis of the hand based on functional and structural abnormalities of sweat glands.
作者信息
Kristiansen Bjørn H, Lindahl Kim H, Pallesen Kristine A U, Bygum Anette
机构信息
Dermatology and Allergy Center, University Hospital of Odense, Odense, Denmark.
Department of Clinical Pathology, University Hospital of Odense, Odense, Denmark.
出版信息
BMJ Case Rep. 2018 Jan 31;2018:bcr-2017-222530. doi: 10.1136/bcr-2017-222530.
A 14-year-old girl and a 30-year-old woman presented with localised hyperhidrosis on the dorsal hand and wrist, respectively, provoked by different stimuli such as physical activity and minor trauma to the skin. The skin was seemingly normal in both patients where an iodine-starch test revealed a well-demarcated area of hyperhidrosis. Following histopathological examination, the diagnosis was unilateral localised hyperhidrosis in both cases; one with normal histology and one with a nevus sudoriferous. Both patients were successfully treated with botulinum toxin type A. The 30-year-old woman additionally used low-dose propantheline bromide periodically and experienced long-term remission on this therapy. Hyperhidrosis may embarrass and interfere with patients' school and careers, and it is therefore important to tailor an effective individual treatment.
一名14岁女孩和一名30岁女性分别在手背和手腕出现局限性多汗症，由不同刺激诱发，如体育活动和皮肤轻微创伤。两名患者的皮肤表面看似正常，碘淀粉试验显示多汗症区域界限清晰。经组织病理学检查，两例诊断均为单侧局限性多汗症；一例组织学正常，另一例伴有汗腺痣。两名患者均成功接受了A型肉毒杆菌毒素治疗。这位30岁的女性还定期使用低剂量溴丙胺太林，并在此治疗下实现了长期缓解。多汗症可能会使患者感到尴尬，并干扰其学业和职业，因此制定有效的个体化治疗方案很重要。
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