Matsumi Yuki, Shirakawa Yasuhiro, Tanabe Shunsuke, Komoto Satoshi, Maeda Naoaki, Ninomiya Takayuki, Noma Kazuhiro, Nishizaki Masahiko, Kagawa Shunsuke, Fujiwara Toshiyoshi
Dept. of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.
Gan To Kagaku Ryoho. 2017 Nov;44(12):1784-1786.
We report a case of an elderly patient with advanced esophageal cancer who underwent multidisciplinary treatment. An 86-year-old male consulted our hospital with complaints of pharynx discomfort and difficulty in swallowing. He was preoperatively diagnosed with esophageal cancer, T3N2M0, Stage III . We performed 2 courses of cisplatin plus 5-FU therapy as neoadjuvant chemotherapy. The primary tumor and metastatic lymph nodes reduced in size, and thoracoscopic esophagectomy in the prone position was performed. Pathological findings were esophageal cancer, pT3-Ad, INF b, ly2, v1, IM0, pPM0, pDM0, pRM1, pN3, pStage III . As the radical margin was positive, chemoradiotherapy was performed. We continued postoperative chemotherapy for approximately 1 year, and the patient has survived without relapse for 4 years from esophagectomy. Even in patients over 80 years old, long-term prognosis can be expected by performing radical surgery and chemoradiotherapy.
我们报告一例接受多学科治疗的老年晚期食管癌患者。一名86岁男性因咽部不适和吞咽困难前来我院就诊。术前诊断为食管癌,T3N2M0,Ⅲ期。我们进行了2个疗程的顺铂联合5-氟尿嘧啶治疗作为新辅助化疗。原发肿瘤和转移淋巴结体积缩小,遂行俯卧位胸腔镜食管切除术。病理结果为食管癌,pT3-Ad,INF b,ly2,v1,IM0,pPM0,pDM0,pRM1,pN3,pⅢ期。由于切缘阳性,进行了放化疗。术后持续化疗约1年,患者自食管切除术后已存活4年无复发。即使是80岁以上的患者,通过根治性手术和放化疗也可获得较好的长期预后。