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使用AtriClip装置进行左心耳封堵:病例系列

Left Atrial Appendage Exclusion Using the AtriClip Device: A Case Series.

作者信息

Page Sarah, Hallam Jane, Pradhan Neelprada, Cowie Brian, Phan Tuong, McGlade Desmond, Rosalion Alex, Newcomb Andrew, Yii Michael

机构信息

Department of Cardiothoracic Surgery, St Vincent's Hospital, Melbourne, Vic, Australia.

Department of Cardiothoracic Surgery, St Vincent's Hospital, Melbourne, Vic, Australia.

出版信息

Heart Lung Circ. 2019 Mar;28(3):430-435. doi: 10.1016/j.hlc.2017.12.006. Epub 2017 Dec 22.

Abstract

BACKGROUND

Atrial fibrillation (AF) affects 1.5-2% of the population and is associated with a five-fold increased lifetime risk of stroke [1]. The left atrial appendage (LAA) is the source of embolic strokes in up to 90% of patients with non-valvular AF with clots in the left atrium [2].

METHODS

We reviewed the clinical notes and echocardiographic findings of 20 patients who underwent open cardiac surgery in which concurrent AtriClip (Atricure Inc, Westchester, OH, USA) device insertion was attempted at our institution from July 2013 to February 2015. This was to examine the safety and efficacy of LAA exclusion with clip devices during open cardiac surgery. Indications for LAA exclusion included a history or suspicion of atrial arrhythmia, left ventricular dilatation, or a history of transient ischaemic attacks.

RESULTS

All 20 of the 20 participants had successful placement of the clip device (100% success rate). There were no adverse events related to the device and no perioperative mortality. There were three late deaths due to chronic obstructive pulmonary disease (COPD), leukaemia, and refractory congestive cardiac failure. No late device related complications were found on follow-up imaging in the remaining patients.

CONCLUSIONS

The results of our study demonstrate the LAA exclusion during open cardiac surgery with the AtriClip device is safe, has a 100% success rate, and appears to be stable over time.

摘要

背景

心房颤动(AF)影响1.5%-2%的人口,并与中风的终生风险增加五倍相关[1]。在高达90%的非瓣膜性AF且左心房有血栓的患者中,左心耳(LAA)是栓塞性中风的来源[2]。

方法

我们回顾了2013年7月至2015年2月在我们机构接受心脏直视手术的20例患者的临床记录和超声心动图检查结果,这些患者同时尝试植入AtriClip(美国俄亥俄州韦斯特切斯特市Atricure公司)装置。目的是检查心脏直视手术期间使用夹子装置排除LAA的安全性和有效性。排除LAA的指征包括有房性心律失常病史或疑似病例、左心室扩张或短暂性脑缺血发作病史。

结果

20名参与者全部成功植入夹子装置(成功率100%)。没有与装置相关的不良事件,也没有围手术期死亡。有3例晚期死亡,分别死于慢性阻塞性肺疾病(COPD)、白血病和难治性充血性心力衰竭。其余患者的随访影像学检查未发现晚期装置相关并发症。

结论

我们的研究结果表明,在心脏直视手术期间使用AtriClip装置排除LAA是安全的,成功率为100%,且随着时间推移似乎是稳定的。

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