Ağca Meltem, Akyıl Fatma Tokgöz, Hörmet Merve, Akman Oğuzhan, Akman Canan, Şen Ayçim, Sevim Tülin
Clinic of Chest Diseases, Süreyyapaşa Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, Turkey.
Department of Radiology, İstanbul University Cerrahpaşa School of Medicine, İstanbul, Turkey.
Turk Thorac J. 2017 Jul;18(3):96-99. doi: 10.5152/TurkThoracJ.2017.16052. Epub 2017 Jul 1.
Pulmonary lymphangitic carcinomatosis (PLC) is defined as infiltration of the lymphatic vessels and perilymphatic connective tissue with tumor cells, which is secondary to malignancy. Therefore, it rarely appears as an initial finding preceding a diagnosis of malignancy. A 30-year-old male patient was hospitalized in our clinic with a pre-diagnosis of interstitial lung disease owing to the complaints of dry cough, progressive dyspnea, and acute respiratory insufficiency. He was diagnosed with signet ring cell carcinoma, which is a histologic subtype of adenocarcinoma, via gastroscopy, and lung involvement was consistent with PLC. Regardless of the patient age, PLC should be considered in differential diagnoses of progressive dyspnea, acute respiratory failure, and widespread interstitial lung involvement.
肺淋巴管癌病(PLC)的定义为肿瘤细胞浸润淋巴管和淋巴管周围结缔组织,它继发于恶性肿瘤。因此,它很少作为恶性肿瘤诊断之前的初始表现出现。一名30岁男性患者因干咳、进行性呼吸困难和急性呼吸功能不全的主诉,在我院门诊以间质性肺疾病的初步诊断入院。通过胃镜检查,他被诊断为印戒细胞癌,这是腺癌的一种组织学亚型,肺部受累符合PLC。无论患者年龄如何,在进行性呼吸困难、急性呼吸衰竭和广泛的间质性肺受累的鉴别诊断中都应考虑PLC。