Joo So Young, Kim June-Bum, Cho Yoon Soo, Cho Yong Suk, Seo Cheong Hoon
Department of Rehabilitation Medicine, Hangang Sacred Heart Hospital, College of Medicine, Hallym University, Seoul, Republic of Korea.
Department of Pediatrics, Hallym University Hangang Sacred Heart Hospital, Seoul, Republic of Korea.
Burns. 2018 Jun;44(4):1005-1010. doi: 10.1016/j.burns.2018.01.011. Epub 2018 Feb 13.
Pruritus, a common, chronically disabling condition is often refractory to treatment. The pruritus sensation is mediated in the spinal cord and post-burn pruritus is considered a form of neuropathic pain. We investigated cold pack therapy as a treatment modality for post-burn pruritus.
We studied 23 patients with severe pruritus scoring at least 5 on the visual analogue scale (VAS) and refractory to antihistamine and gabapentin administration. Each cold pack therapy lasted more than 20min. Patients participated in more than three sessions daily for 4 consecutive weeks. The numerical rating scale (NRS), 5-D Itch Scale, Leuven Itch Scale, and perfusion units were evaluated before, within 30min after, 2, and 4 weeks cold pack therapy.
In all patients, the NRS was 9.37±1.47 pre-therapy, 3.48±2.19 at 2 weeks, and 2.78±2.13 at 4 weeks following therapy, the pre-scores being significantly different (p<0.001). Pruritus severity and consequences scores (Leuven Itch Scale) were improved after therapy compared to pre-therapy. Perfusion unit (PU) scores were statistically insignificant compared to PU scores measured before the application of cold pack therapy. Degree, direction, and disability scores (5-D Itch scale) significantly differed (p<.05).
Cold pack therapy, a non-invasive, non-pharmacological treatment modality significantly reduces post-burn pruritus and could be useful in burn patients.
瘙痒是一种常见的、长期使人丧失能力的病症,治疗往往难以奏效。瘙痒感在脊髓中传导,烧伤后瘙痒被认为是神经性疼痛的一种形式。我们研究了冷敷疗法作为烧伤后瘙痒的一种治疗方式。
我们研究了23例严重瘙痒患者,其视觉模拟量表(VAS)评分至少为5分,且对组胺药和加巴喷丁治疗无效。每次冷敷疗法持续超过20分钟。患者连续4周每天参加超过3次治疗。在冷敷治疗前、治疗后30分钟内、2周和4周时评估数字评分量表(NRS)、5-D瘙痒量表、鲁汶瘙痒量表和灌注单位。
所有患者治疗前NRS评分为9.37±1.47,治疗2周时为3.48±2.19,治疗4周时为2.78±2.13,治疗前评分有显著差异(p<0.001)。与治疗前相比,治疗后瘙痒严重程度和后果评分(鲁汶瘙痒量表)有所改善。与冷敷治疗前测量的灌注单位(PU)评分相比,PU评分在统计学上无显著差异。程度、方向和残疾评分(5-D瘙痒量表)有显著差异(p<.05)。
冷敷疗法作为一种非侵入性、非药物治疗方式,能显著减轻烧伤后瘙痒,对烧伤患者可能有用。