Dawani Om, Khan Raja Samir, Syed Mujtaba Jamal, Shehzad Abdul Moid, Alratoot Ahmed, Ahmed Muhammad Faizan
1 Internal Medicine Resident, Michigan State University, East Lansing, MI, USA.
2 Research Associate, Aga Khan University, Karachi, Pakistan.
Trop Doct. 2018 Jul;48(3):232-234. doi: 10.1177/0049475518757625. Epub 2018 Feb 16.
For many years, tuberculosis (TB) has been endemic in Pakistan; many rare and unusual presentations have been reported. There is a myriad of non-specific symptoms which always requires a high index of clinical suspicion for TB. World Health Organization data suggest that Pakistan ranks as the fifth highest country burdened with TB and has the fourth highest prevalence of multi-drug resistant TB globally. With an annual incidence of 277 cases per 100,000, the importance of early diagnosis and treatment is self-evident. We present a case where a strong suspicion of isolated hepatosplenic TB in an immunocompetent patient justified a directed approach.
多年来，结核病在巴基斯坦一直呈地方流行状态；已有许多罕见和不寻常表现的报道。存在大量非特异性症状，这始终需要对结核病有高度的临床怀疑指数。世界卫生组织的数据表明，巴基斯坦是结核病负担第五高的国家，且在全球耐多药结核病患病率方面排名第四。每年每10万人中有277例发病，早期诊断和治疗的重要性不言而喻。我们报告一例病例，一名免疫功能正常的患者被高度怀疑患有孤立性肝脾结核，这证明了采取针对性方法的合理性。
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