Al Wakeel Jamal Saleh, Al Ghonaim Mohammed A, Aldohayan Abdullah, Usama Saira, Al Obaili Saad, Tarakji Ahmad R, Alkhowaiter Mohammad
Department of Medicine, Nephrology Unit, King Saud University, Riyadh, Saudi Arabia.
Saudi J Kidney Dis Transpl. 2018 Jan-Feb;29(1):71-80. doi: 10.4103/1319-2442.225197.
Our objective is to study the outcomes and complications of peritoneal dialysis (PD) including comparison of self-care PD with home-care assisted PD during a five-year period. A retrospective study of PD data at King Saud University-affiliated hospital in Riyadh from January 1, 2009, to December 31, 2013. One hundred and eleven patients were included (female 55%). The average age was 47.4 (1-83) years. Twenty-one (18.91%) patients were on continuous ambulatory PD and 90 (81.08%) on automated PD. The mean time on PD was 23.5 (3-60) months. At the end of five years, 47 (42.34%) patients were continuing on PD, 12 (10.81%) had renal transplant, 33 (29.73%) patients were transferred to hemodialysis, and two (1.8%) patients were transferred to other centers. Seventeen patients died during this period giving a mortality rate of 7.13 deaths/100 patient-year during the five-year period. Six patients died due to cardiovascular causes, while five had sepsis. There was one death each due to prostate cancer, hyperoxaluria, and toxic epidermal necrolysis. Three patients died suddenly at home. Peritonitis rate was one episode/35.28 patient/month or one episode/2.94 patient/year. We compared the results for patients doing the dialysis themselves [56 (50.45%)] "self-care PD" to 55 (49.5%) patients assisted by a family member or other caregivers "assisted PD." We found no significant difference in the incidence of complications, technical outcome, mortality, and peritonitis episodes. However, we found a high prevalence of diabetes mellitus and significant increase in exit site infection in assisted PD. Our study suggests that PD patients in Saudi Arabia have a good overall outcome. Furthermore, assisted PD showed good patient and technique outcome.
我们的目标是研究腹膜透析(PD)的治疗结果和并发症,包括在五年期间比较自我护理腹膜透析和家庭护理辅助腹膜透析。对利雅得沙特国王大学附属医院2009年1月1日至2013年12月31日期间的腹膜透析数据进行回顾性研究。共纳入111例患者(女性占55%)。平均年龄为47.4(1 - 83)岁。21例(18.91%)患者接受持续性非卧床腹膜透析,90例(81.08%)接受自动化腹膜透析。腹膜透析的平均时间为23.5(3 - 60)个月。五年结束时,47例(42.34%)患者继续接受腹膜透析,12例(10.81%)接受了肾移植,33例(29.73%)患者转为血液透析,2例(1.8%)患者转至其他中心。在此期间有17例患者死亡,五年期间的死亡率为7.13例死亡/100患者年。6例患者死于心血管原因,5例死于败血症。分别有1例死于前列腺癌、高草酸尿症和中毒性表皮坏死松解症。3例患者在家中突然死亡。腹膜炎发生率为1次发作/35.28患者/月或1次发作/2.94患者/年。我们将自行进行透析的患者[56例(50.45%)]“自我护理腹膜透析”与由家庭成员或其他护理人员辅助的55例(49.5%)患者“辅助腹膜透析”的结果进行了比较。我们发现并发症发生率、技术结果、死亡率和腹膜炎发作次数方面无显著差异。然而,我们发现糖尿病患病率较高,且辅助腹膜透析患者出口处感染显著增加。我们的研究表明,沙特阿拉伯的腹膜透析患者总体预后良好。此外,辅助腹膜透析显示出良好的患者和技术结果。