Shigematsu-Locatelli Marie, Kawano Takashi, Nishigaki Atsushi, Yamanaka Daiki, Aoyama Bun, Tateiwa Hiroki, Kitaoka Noriko, Yokoyama Masataka
Department of Anesthesiology and Intensive Care Medicine, Kochi Medical School, Kohasu, Oko-cho, Nankoku, Kochi 783-8505 Japan.
JA Clin Rep. 2017;3(1):27. doi: 10.1186/s40981-017-0099-0. Epub 2017 May 10.
The major perioperative concern in patients with second-degree atrioventricular (AV) block is the progression to complete AV block. Therefore, the prophylactic implantation of a temporary pacemaker prior to surgery is recommended, especially in symptomatic patients. However, as no quantitative preoperative risk assessment from progression to complete AV block is available, there is currently no established indication for preoperative prophylactic pacemaker implantation. Here, we present a case of progression from asymptomatic second-degree two-to-one (2:1) AV block to complete AV block following the induction of general anesthesia.
A 69-year-old female with degenerative spinal stenosis was scheduled for transforaminal lumbar interbody fusion surgery under general anesthesia. She had no cardiac symptoms, but routine preoperative resting 12-lead electrocardiogram revealed second-degree 2:1 AV block. After discussion with the surgeon and referring cardiologist, we scheduled the surgery without implantation of a temporary pacemaker before surgery for the following reasons: (1) asymptomatic, (2) no evidence of underlying cardiac disease, and (3) a narrow QRS complex. On the day of surgery, general anesthesia was induced with 150 mg of intravenous thiamylal and 25 μg of fentanyl, followed by intravenous administration of 50 mg of rocuronium to facilitate endotracheal intubation. Sevoflurane (1.0-2.0%) was used to maintain anesthesia. A few minutes after induction, the 2:1 AV block progressively converted to complete AV block, and the surgery was postponed. During emergence from anesthesia, the third-degree AV block recovered to 2:1 AV block, similar with the preoperative pattern. The patient was monitored in the intensive care unit for 2 days and then transferred to the normal orthopedic ward uneventfully. One month later, the surgery was rescheduled with preoperative implantation of a temporary pacemaker. A slow mask induction using sevoflurane with oxygen was started. Upon loss of consciousness during the inhalation of initial sevoflurane, complete AV block developed and temporary pacing was immediately initiated. Subsequent anesthesia and surgery were uneventful. The patient made an uncomplicated recovery from surgery with stable hemodynamics. The temporary pacemaker was not required after surgery, and the pacemaker catheter was removed 1 day after surgery.
The present case indicates that a prophylactic pacemaker should be implanted preoperatively in patients who have 2:1 AV block even without symptoms.
二度房室传导阻滞患者围手术期主要关注的问题是进展为完全性房室传导阻滞。因此,建议在手术前预防性植入临时起搏器,尤其是有症状的患者。然而,由于目前尚无从进展为完全性房室传导阻滞的术前定量风险评估方法,目前尚无术前预防性起搏器植入的既定指征。在此,我们报告一例在全身麻醉诱导后从无症状的二度2:1房室传导阻滞进展为完全性房室传导阻滞的病例。
一名69岁患有退行性腰椎管狭窄症的女性计划在全身麻醉下进行经椎间孔腰椎椎间融合术。她没有心脏症状,但术前常规静息12导联心电图显示二度2:1房室传导阻滞。在与外科医生和会诊心脏病专家讨论后,我们因以下原因在术前未植入临时起搏器的情况下安排了手术:(1)无症状;(2)无潜在心脏病证据;(3)QRS波群狭窄。手术当天,静脉注射150mg硫喷妥钠和25μg芬太尼诱导全身麻醉,随后静脉注射50mg罗库溴铵以利于气管插管。使用七氟醚(1.0 - 2.0%)维持麻醉。诱导后几分钟,2:1房室传导阻滞逐渐转变为完全性房室传导阻滞,手术推迟。在麻醉苏醒期间,三度房室传导阻滞恢复为2:1房室传导阻滞,与术前模式相似。患者在重症监护病房监测2天,然后顺利转入普通骨科病房。一个月后,重新安排手术并在术前植入临时起搏器。开始使用七氟醚和氧气进行缓慢面罩诱导。在最初吸入七氟醚期间意识丧失时,发生了完全性房室传导阻滞,立即开始临时起搏。随后的麻醉和手术过程顺利。患者术后恢复顺利,血流动力学稳定。术后不需要临时起搏器,术后1天拔除起搏器导管。
本病例表明,即使无症状,二度2:1房室传导阻滞患者术前也应植入预防性起搏器。