儿童人群中的 A 组链球菌性脑脓肿：病例系列及文献复习。
Group A Streptococcal Brain Abscess in the Pediatric Population: Case Series and Review of the Literature.
机构信息
From the Division of Pediatric Emergency Medicine, Department of Pediatrics.
Pediatric Infectious Disease Unit, Dana-Dwek Children's Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
出版信息
Pediatr Infect Dis J. 2018 Oct;37(10):967-970. doi: 10.1097/INF.0000000000001947.
BACKGROUND
Group A Streptococcus (GAS) is a rare cause of central nervous system infections.
METHODS
We describe 3 new cases of GAS brain abscess in previously healthy children treated by us between 2015 and 2016 and review the 5 cases reported in the literature since 1988.
RESULTS
All 8 children received early empiric antibiotic therapy and surgical intervention, and 5 made a full recovery.
CONCLUSIONS
GAS brain abscess is a rare infection; however its incidence may be rising. We suggest that if patients show symptoms such as fever, vomiting and lethargy, with contiguous infection such as otitis media, mastoiditis, sinusitis or meningitis, GAS brain abscess should be suspected. Prognosis is expected to be good with early implementation of appropriate treatment.
背景
A 组链球菌（GAS）是引起中枢神经系统感染的罕见病因。
方法
我们描述了 3 例新的 GAS 脑脓肿病例，这些患者在 2015 年至 2016 年期间由我们治疗，且均为既往健康的儿童，同时我们还回顾了自 1988 年以来文献中报道的 5 例病例。
结果
所有 8 例患儿均接受了早期经验性抗生素治疗和手术干预，5 例患儿完全康复。
结论
GAS 脑脓肿是一种罕见的感染；然而，其发病率可能正在上升。我们建议，如果患者出现发热、呕吐和嗜睡等症状，同时伴有相邻部位感染，如中耳炎、乳突炎、鼻窦炎或脑膜炎，应怀疑 GAS 脑脓肿。如果早期实施适当的治疗，预后预计良好。
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