Langlais F
Presse Med. 1986 Nov 8;15(39):1967-70.
Resection of primary malignant bone tumours, followed by reconstruction and functional preservation of the limbs, seems to give oncological results that are at least equivalent to those of radical amputation surgery. The psychological and functional benefits are obvious: 30% of the patients operated upon recover with a very satisfactory function and resume professional activities or even games; 60% revert to their previous familial and social activities, and 10% only remain severely handicapped. However, numerous problems still have to be solved: the value of this conservative surgery must be demonstrated statistically; the incidence of its complications, notably in the knee, must be reduced; the fate of homografts must be known; its indications must be extended by improving its results in areas where these are still uncertain (e.g. pelvis, lower end of the leg) or functionally mediocre (shoulder). Only comparisons within study groups, either national (such as the PETAL group), or international (such as the Muscule Skelatal Tumor Society), can provide positive answers in a field where question marks are more frequent than certainties.
原发性恶性骨肿瘤切除术后进行肢体重建和功能保留,其肿瘤学效果似乎至少与根治性截肢手术相当。心理和功能方面的益处显而易见:30%接受手术的患者功能恢复非常满意,能够恢复职业活动甚至运动;60%能够恢复之前的家庭和社交活动,只有10%仍严重残疾。然而,仍有许多问题有待解决:这种保肢手术的价值必须通过统计学证明;其并发症的发生率,尤其是在膝关节,必须降低;同种异体移植的转归必须明确;必须通过改善在结果仍不确定的部位(如骨盆、小腿下端)或功能一般的部位(肩部)的手术效果来扩大其适应证。只有在国家层面(如PETAL组)或国际层面(如肌肉骨骼肿瘤学会)的研究组内进行比较,才能在这个疑问多于定论的领域给出肯定答案。